PTK7 and TNFRSF21

Data Source:
BioGRID (affinity chromatography technology)

		PTK7	TNFRSF21
Description		protein tyrosine kinase 7 (inactive)	TNF receptor superfamily member 21
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Intrinsic Component Of Plasma Membrane
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Protein Binding
	Biological Process	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	B Cell Apoptotic Process Adaptive Immune Response Apoptotic Process Humoral Immune Response Axonal Fasciculation Viral Process Regulation Of Lipid Metabolic Process Negative Regulation Of B Cell Proliferation Negative Regulation Of Myelination Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Negative Regulation Of T Cell Proliferation Myelination Regulation Of Oligodendrocyte Differentiation T Cell Receptor Signaling Pathway Neuron Apoptotic Process Cellular Response To Tumor Necrosis Factor Oligodendrocyte Apoptotic Process
Pathways			PPARA activates gene expression
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Panic disorder ( 19165232) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
Interacting Genes		38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2	7 interacting genes: CLIP3 MATR3 NSD1 SGTA STX11 TRADD WASH2P
Entrez ID		5754	27242
HPRD ID		03534	05759
Ensembl ID		ENSG00000112655	ENSG00000146072
Uniprot IDs		Q13308	A0A024RD71 O75509
PDB IDs		6VG3	2DBH 3QO4 3U3P 3U3Q 3U3S 3U3T 3U3V
Enriched GO Terms of Interacting Partners?
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