MIF4GD and SVIL

Data Source:
BioGRID (two hybrid)

		MIF4GD	SVIL
Description		MIF4G domain containing	supervillin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Golgi Apparatus Cytosol	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere
	Molecular Function	RNA Binding Protein Binding Protein C-terminus Binding Translation Activator Activity Identical Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding
	Biological Process	Regulation Of Translational Initiation Positive Regulation Of Translation	Skeletal Muscle Tissue Development Actin Polymerization Or Depolymerization Positive Regulation Of Cytokinesis Actin Filament Severing Barbed-end Actin Filament Capping
Pathways
Drugs
Diseases
GWAS			Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155) Plateletcrit ( 32888494)
Interacting Genes		23 interacting genes: AQP1 ATPAF2 CFAP206 CHCHD2 CRYBA4 CTIF DDIAS DDX19A DDX19B EIF3G ENKD1 EXOSC6 FAM110A HDAC4 HGS HINFP MKRN3 NTAQ1 PDE4DIP PPARG SMARCB1 SVIL UBQLN4	35 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		57409	6840
HPRD ID		10629	04992
Ensembl ID		ENSG00000125457	ENSG00000197321
Uniprot IDs		A0A0S2Z5K9 A0A0S2Z5S7 A0A0S2Z5T5 A0A3B3IU65 A9UHW6	A0A6I8PIX7 O95425 Q569J5
PDB IDs			2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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