SVIL and ODF2

Data Source:
BioGRID (two hybrid)

		SVIL	ODF2
Description		supervillin	outer dense fiber of sperm tails 2
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere	Spindle Pole Outer Dense Fiber Nucleus Centrosome Centriole Cytosol Microtubule Sperm Flagellum Ciliary Transition Fiber Centriolar Subdistal Appendage
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding	Structural Molecule Activity Protein Binding
	Biological Process	Skeletal Muscle Tissue Development Actin Polymerization Or Depolymerization Positive Regulation Of Cytokinesis Actin Filament Severing Barbed-end Actin Filament Capping	G2/M Transition Of Mitotic Cell Cycle Multicellular Organism Development Spermatid Development Protein Localization Regulation Of G2/M Transition Of Mitotic Cell Cycle Centriole-centriole Cohesion Cilium Organization Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155) Plateletcrit ( 32888494)	Body mass index ( 26426971)
Interacting Genes		35 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG	16 interacting genes: APP FBXO25 ING5 LRRK1 MAP3K1 MARK4 MEOX2 ODF1 RAB8A SMURF1 SNW1 SVIL TRAF5 TRIM55 TRIM63 ZDHHC17
Entrez ID		6840	4957
HPRD ID		04992	03601
Ensembl ID		ENSG00000197321	ENSG00000136811
Uniprot IDs		A0A6I8PIX7 O95425 Q569J5	A0A024R8A4 A0A024R8A5 B3KSD5 B4DUU0 B4DX03 B4DX85 Q5BJF6
PDB IDs		2K6M 2K6N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?