MIR18B and CPSF6

Data Source:
BioGRID (unspecified method)

		MIR18B	CPSF6
Description		microRNA 18b	cleavage and polyadenylation specific factor 6
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Perichromatin Fibrils Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane Nuclear Speck Interchromatin Granule Paraspeckles Ribonucleoprotein Complex
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding MRNA Binding Protein Binding Ribosomal Large Subunit Binding Exon-exon Junction Complex Binding
	Biological Process	Negative Regulation Of Epithelial Cell Differentiation Gene Silencing By MiRNA	MRNA Processing Positive Regulation Of RNA Export From Nucleus Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly
Pathways			Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease
Drugs
Diseases
GWAS			Height ( 18391951) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Pneumoconiosis in silica exposure ( 24986923) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		84 interacting genes: APOBEC3B C1QBP CELF1 CELF2 CPSF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 EIF2AK2 EPRS1 FAM98A FAM98B FUS GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUDT21 P3H1 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SYNCRIP TAF15 TRA2B TRIM26 TRIM71 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	48 interacting genes: APBB1 ARMC7 CSNK2A1 EWSR1 GIN1 ITCH ITSN2 KLHL12 MIR10B MIR128-1 MIR128-2 MIR138-2 MIR155 MIR17 MIR18B MIR199A1 MIR19A MIR19B1 MIR19B2 MIR25 MIR29A MIR34A MIR92A1 MIR93 MIRLET7A1 MIRLET7B MIRLET7C MIRLET7D MIRLET7F2 NCK2 NEDD4 NUDT21 OTUB2 PLSCR1 PPIL1 PRPF40A SRSF7 TCERG1 TOLLIP UBAC1 UBQLN4 USP21 WBP4 WWOX WWP1 WWP2 YES1 ZMYND19
Entrez ID		574033	11052
HPRD ID			05401
Ensembl ID		ENSG00000283931	ENSG00000111605
Uniprot IDs			Q16630
PDB IDs			3P5T 3P6Y 3Q2S 3Q2T 4B4N 4U0A 4U0B 4WYM 6AY9 6GX9
Enriched GO Terms of Interacting Partners?
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