CPSF6 and ZMYND19

Data Source:
BioGRID (two hybrid)

		CPSF6	ZMYND19
Description		cleavage and polyadenylation specific factor 6	zinc finger MYND-type containing 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Perichromatin Fibrils Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane Nuclear Speck Interchromatin Granule Paraspeckles Ribonucleoprotein Complex	Cytoplasm Plasma Membrane Synapse
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosomal Large Subunit Binding Exon-exon Junction Complex Binding	Protein Binding Metal Ion Binding
	Biological Process	MRNA Processing Positive Regulation Of RNA Export From Nucleus Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease
Drugs
Diseases
GWAS		Height ( 18391951) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Pneumoconiosis in silica exposure ( 24986923) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)	Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Systolic blood pressure ( 30578418)
Interacting Genes		48 interacting genes: APBB1 ARMC7 CSNK2A1 EWSR1 GIN1 ITCH ITSN2 KLHL12 MIR10B MIR128-1 MIR128-2 MIR138-2 MIR155 MIR17 MIR18B MIR199A1 MIR19A MIR19B1 MIR19B2 MIR25 MIR29A MIR34A MIR92A1 MIR93 MIRLET7A1 MIRLET7B MIRLET7C MIRLET7D MIRLET7F2 NCK2 NEDD4 NUDT21 OTUB2 PLSCR1 PPIL1 PRPF40A SRSF7 TCERG1 TOLLIP UBAC1 UBQLN4 USP21 WBP4 WWOX WWP1 WWP2 YES1 ZMYND19	52 interacting genes: ANKRD55 C19orf54 CBWD1 CBWD3 CBWD5 CCNI CEACAM6 CPSF6 DTX3 ENOX1 FIP1L1 FNDC3B GAPDHS GGN GMEB2 GORASP2 GRB10 GSE1 GTF2F2 HACL1 HOMEZ INCA1 KCTD13 KCTD21 LZTS1 LZTS2 MCHR1 MLLT6 NAB2 PNMA5 PPP1R37 PRKAB2 PRKAR1B PRMT5 PSMA1 PTGES3L-AARSD1 RFX6 SAXO1 SCN5A SELENOV SS18L1 TBRG1 TNFAIP1 TNNT1 TOLLIP TOX4 TRIM27 TRIM45 TUBB WDR77 ZBTB2 ZXDC
Entrez ID		11052	116225
HPRD ID		05401	15743
Ensembl ID		ENSG00000111605	ENSG00000165724
Uniprot IDs		Q16630	Q96E35
PDB IDs		3P5T 3P6Y 3Q2S 3Q2T 4B4N 4U0A 4U0B 4WYM 6AY9 6GX9
Enriched GO Terms of Interacting Partners?
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