CBX8 and RPTOR

CBX8

RPTOR

Description chromobox 8 regulatory associated protein of MTOR complex 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain morphology (MOSTest) ( 32665545)
  • General risk tolerance (MTAG) ( 30643258)
  • Plateletcrit ( 32888494)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Youthful appearance (self-reported) ( 32339537)
  • Adult body size ( 32376654)
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413)
  • Body size at age 10 ( 32376654)
  • Hypertension ( 30487518)
  • Mean arterial pressure ( 30487518)
  • NASH resolution in nonalcoholic steatohepatitis ( 31832568)
  • Nicotine dependence symptom count ( 25555482)
  • Obesity ( 23563607)
  • Pulse pressure ( 29403010 30487518)
  • Systolic blood pressure ( 30487518)
Interacting Genes 87 interacting genes: ABLIM3 BACH2 BANP BMI1 CALCOCO2 CARD10 CARD9 CCDC136 CCDC57 CEP70 DVL3 EEF1G FHL3 FSD2 FXR1 GIGYF1 GOLGA2 GOLGA6L9 GPRASP2 GRIPAP1 H3-4 HAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 JADE2 JAKMIP1 KANK2 KAT5 KAT7 KCTD9 KIFC3 KRT31 KRT34 KRT40 LSM2 LZTS2 MB21D2 MCC MDFI MID2 MLLT1 MLLT3 MTUS2 NAB2 PAXIP1 PCGF5 PHACTR1 PIBF1 PICK1 PIH1D2 PLEKHF2 PNMA1 PNMA2 POLR1C PRDM6 PRKAR1B RASSF3 RING1 RPGRIP1 SESTD1 SETDB1 SOX5 TAX1BP1 TEPSIN TFCP2 TFIP11 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC22D4 TSGA10 TTC23 UNC119 USH1G USP11 USP7 VIM ZBTB14 ZBTB8A ZBTB9 ZNF185 ZRANB1 23 interacting genes: CILK1 DUXAP9 EIF4EBP1 EIF4EBP2 IRS1 IRS2 LINC00839 MAPK1 MAPK3 MARK4 MLST8 MTOR NRBF2 PLD2 PRKAA1 PRKAA2 RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB WIPI2
Entrez ID 57332 57521
HPRD ID 13006 06184
Ensembl ID ENSG00000141570 ENSG00000141564
Uniprot IDs Q9HC52 Q6DKI0 Q8N122
PDB IDs 2N4Q 3I91 5EQ0 5H64 6BCU 6BCX 6SB0 6SB2 6U62
Enriched GO Terms of Interacting Partners?
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