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TMPRSS4 and CLEC7A
Data Source:
BioGRID
(two hybrid)
TMPRSS4
CLEC7A
Description
transmembrane serine protease 4
C-type lectin domain containing 7A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
Integral Component Of Membrane
Secretory Granule
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Serine-type Endopeptidase Activity
Scavenger Receptor Activity
Protein Binding
Serine-type Peptidase Activity
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Metal Ion Binding
Biological Process
Proteolysis
Endocytosis
Response To Wounding
Regulation Of Gene Expression
Protein Processing
Negative Regulation Of Growth Rate
Positive Regulation Of Viral Entry Into Host Cell
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Cytokine Production
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Population Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Defense Response To Protozoan
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Innate Immune Response
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Phagocytosis
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Killing Of Cells Of Other Organism
Positive Regulation Of Respiratory Burst
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Pathways
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Interacting Genes
14 interacting genes:
BNIP3L
CLEC7A
CLRN1
ERVFRD-1
FAM209A
FNDC9
GPX8
KASH5
LMNA
RASGRP4
SIGLEC12
SUSD3
SYNE4
TMEM79
47 interacting genes:
ADAM33
AIP
ARL13B
ASGR2
BNIP3
BNIP3L
C14orf180
CALM3
CD53
CD74
CTXN3
CXCL9
FAM3A
FCGR1A
FNDC9
GJB1
HSPD1
IFNGR2
IL1RL1
JAGN1
KLRC1
KTN1
MTIF3
NEMP1
NINJ2
NSG2
OCLN
OLFM4
OPRM1
PTTG1IP
RANBP9
RHOU
SAR1A
SEC22A
SGCB
SMIM3
SPINT1
SUSD3
SYNE4
TEX29
TLCD4
TMEM79
TMPRSS2
TMPRSS4
UPK2
VSIR
ZFPL1
Entrez ID
56649
64581
HPRD ID
05952
08396
Ensembl ID
ENSG00000137648
ENSG00000172243
Uniprot IDs
B7Z458
B7Z8X1
B7Z900
Q9NRS4
A0A024RAN9
A0A0S2Z5Q1
Q68D78
Q9BXN2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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