CCL28 and XCL2

Data Source:
BioGRID (pull down)

		CCL28	XCL2
Description		C-C motif chemokine ligand 28	X-C motif chemokine ligand 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Chemotaxis Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling	Monocyte Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Circulation Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		Metabolite levels (X-11787) ( 23934736) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		26 interacting genes: ACKR2 CCL11 CCL13 CCL17 CCL21 CCL26 CCL5 CCR10 CCR3 CXCL10 CXCL12 CXCL13 CXCL14 CXCL17 CXCL2 CXCL9 DDI1 DYNLT3 PF4 PF4V1 PPBP PSMA3 STUB1 TSC1 XCL1 XCL2	19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1
Entrez ID		56477	6846
HPRD ID		05577	05317
Ensembl ID		ENSG00000151882	ENSG00000143185
Uniprot IDs		A0N0Q3 D6RC73 Q9NRJ3	Q9UBD3
PDB IDs		6CWS
Enriched GO Terms of Interacting Partners?
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