PRMT8 and CEP162

Data Source:
BioGRID (two hybrid)

		PRMT8	CEP162
Description		protein arginine methyltransferase 8	centrosomal protein 162
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Anchored Component Of The Cytoplasmic Side Of The Plasma Membrane	Nucleus Centrosome Centriole Spindle Cytosol Axonemal Microtubule
	Molecular Function	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Enzyme Binding Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Identical Protein Binding Protein Homodimerization Activity S-adenosyl-L-methionine Binding	Protein Binding
	Biological Process	Protein Methylation Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone Arginine Methylation Regulation Of Protein Binding Protein Homooligomerization	Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 31014085) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Gut microbiota (bacterial taxa) ( 27723756) HDL cholesterol ( 19060911)	Diabetic retinopathy in type 2 diabetes ( 25364816)
Interacting Genes		22 interacting genes: CARM1 CEP162 COIL DCAF8 EWSR1 FBL FYN GPATCH2L H4C1 KRTAP6-3 OFCC1 PIK3R1 PLCG1 PPARA PRMT1 PRMT2 SERBP1 SYNCRIP TNPO2 UBL5 VHL ZNF451	7 interacting genes: CPNE4 KDM1A MTDH PRMT1 PRMT8 SPP1 YEATS4
Entrez ID		56341	22832
HPRD ID		11029	10796
Ensembl ID		ENSG00000111218	ENSG00000135315
Uniprot IDs		Q59GT2 Q9NR22	Q5TB80
PDB IDs		4X41 5DST
Enriched GO Terms of Interacting Partners?
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