PRKCD and PTPN22

  • Data Source:
  • HPRD (in vivo, in vitro)

PRKCD

PTPN22

Description protein kinase C delta protein tyrosine phosphatase non-receptor type 22
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 21926972)
  • Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083)
  • Ulcerative colitis ( 23128233)
  • Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes 120 interacting genes: ACTA1 ACTA2 ACTB ADAM9 ADCY7 ADD1 ADD2 ADRA2A ADRB2 AFAP1 AKT3 APP ART3 BDKRB2 C1QBP CD34 CDCP1 CHAT CNP CREBBP CYTH1 DAB2 DYNC1H1 EEF1A1 EGFR EIF2S1 ELAVL1 EP300 ESRRA FLI1 FSCN1 FYN GABRA1 GAP43 GNA12 GNA13 GNAZ GRK2 GRM5 GSK3A H1-1 H1-5 HABP4 HDAC5 HNRNPK HSP90AA1 HSPA4 IGF1R IKBKB IL6ST INSR IRS1 ITGA6 ITGB2 ITGB4 ITGB7 ITPR1 KCNJ1 KCNJ4 KLF5 LCK LMNB1 LMNB2 LYN MACF1 MAPK1 MAPK3 MAPT MBP MEP1B MS4A2 MUC1 NCF1 NCF4 NFE2L2 NOTCH1 NUMB OPRD1 PAK1 PDP1 PDP2 PDPK1 PEBP1 PIK3CA PIK3CB PLCB1 PLD2 PLSCR1 PLSCR3 PPARA PPM1A PPP1CA PPP2CA PPP2R5C PRKCZ PRKDC PTK2B PTPN22 PTPN6 PTPRA RAC1 RACK1 RAF1 RASGRP3 RIPK4 RUNX2 SDC4 SHC1 SPRY2 SQSTM1 SRC STAT1 STAT3 TAGLN TIAM1 TNFRSF1A VCP YWHAB YWHAG YWHAZ 12 interacting genes: CBL CD247 CD3E CLK1 CSK EGFR GRB2 LCK PRKCD SRPK2 VAV1 ZAP70
Entrez ID 5580 26191
HPRD ID 01501 06100
Ensembl ID ENSG00000163932 ENSG00000134242
Uniprot IDs A0A024R328 B4DFV1 Q05655 B4DZW8 G3K0T4 Q9Y2R2
PDB IDs 1YRK 2YUU 2P6X 2QCJ 2QCT 3BRH 3H2X 3OLR 3OMH 4J51
Enriched GO Terms of Interacting Partners?
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