PRKAG1 and SHMT2

  • Data Source:
  • BioGRID (biochemical)

PRKAG1

SHMT2

Description protein kinase AMP-activated non-catalytic subunit gamma 1 serine hydroxymethyltransferase 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 28 interacting genes: ACACA AP1S3 C1orf94 CBS EIF3G KCNN4 KEAP1 KRTAP1-1 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP4-12 KRTAP4-2 KRTAP9-2 KRTAP9-8 MEOX1 MEOX2 PAICS PAX6 PLEKHF2 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG2 TEKT1 TNFAIP1 18 interacting genes: ABRAXAS2 APP ARL6IP1 BABAM1 BABAM2 BRCC3 CAB39 CLEC2D CMTM5 CREB3 CSNK2B DUX4 ESR1 FBXO7 KASH5 MAL2 NDRG1 PPARD
Entrez ID 5571 6472
HPRD ID 04118 00717
Ensembl ID ENSG00000181929 ENSG00000182199
Uniprot IDs A0A024R125 P54619 A0A024RB99 B4DJQ3 B4DLV4 P34897 Q5BJF5 Q5HYG8 V9HW06
PDB IDs 2UV4 2UV5 2UV6 2UV7 4CFE 4CFF 4RER 4REW 4ZHX 5EZV 5ISO 6B1U 6B2E 6C9F 6C9G 6C9H 6C9J 4PVF 5V7I 5X3V 6DK3 6H3C 6QVG 6QVL 6R8F
Enriched GO Terms of Interacting Partners?
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