PRKAG1 and KRTAP10-11

Data Source:
BioGRID (two hybrid)

		PRKAG1	KRTAP10-11
Description		protein kinase AMP-activated non-catalytic subunit gamma 1	keratin associated protein 10-11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nucleotide-activated Protein Kinase Complex	Cytosol Keratin Filament
	Molecular Function	Protein Kinase Activity CAMP-dependent Protein Kinase Activity Protein Binding ATP Binding CAMP-dependent Protein Kinase Regulator Activity AMP Binding Protein Kinase Regulator Activity Protein Kinase Binding ADP Binding	Protein Binding
	Biological Process	Regulation Of Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Cell Cycle Arrest Signal Transduction Spermatogenesis Positive Regulation Of Gene Expression Macroautophagy Regulation Of Macroautophagy Cellular Response To Glucose Starvation Positive Regulation Of Protein Kinase Activity Regulation Of Catalytic Activity Import Into Nucleus Regulation Of Signal Transduction By P53 Class Mediator Regulation Of CAMP-dependent Protein Kinase Activity	Keratinization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs	Keratinization Keratinization
Drugs		Adenosine phosphate Acetylsalicylic acid Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder ( 31043756) Body mass index ( 29273807) HDL cholesterol ( 30275531) Pulse pressure ( 27618447) Red cell distribution width ( 32888494) Systolic blood pressure ( 27618447 30578418)
Interacting Genes		28 interacting genes: ACACA AP1S3 C1orf94 CBS EIF3G KCNN4 KEAP1 KRTAP1-1 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP4-12 KRTAP4-2 KRTAP9-2 KRTAP9-8 MEOX1 MEOX2 PAICS PAX6 PLEKHF2 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG2 TEKT1 TNFAIP1	38 interacting genes: ADAMTSL4 ANKS1A C22orf39 CAMK2B CATSPER1 CREB5 CYSRT1 FAM76B FBXO34 GLRX3 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP13-3 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1B LCE1D LCE1E LCE3B LCE3C MEOX2 MOBP NOTCH2NLA OTX1 PLSCR1 POU4F2 PRKAB2 PRKAG1 SMCP SPATA3 SPRY1 SPRY2 TLE5 ZNF587
Entrez ID		5571	386678
HPRD ID		04118	11186
Ensembl ID		ENSG00000181929	ENSG00000243489
Uniprot IDs		A0A024R125 P54619	P60411 P60412
PDB IDs		2UV4 2UV5 2UV6 2UV7 4CFE 4CFF 4RER 4REW 4ZHX 5EZV 5ISO 6B1U 6B2E 6C9F 6C9G 6C9H 6C9J
Enriched GO Terms of Interacting Partners?
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