PRKACG and TNP2

Data Source:
BioGRID (enzymatic study)

		PRKACG	TNP2
Description		protein kinase cAMP-activated catalytic subunit gamma	transition protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Ciliary Base	Nucleosome Nucleus
	Molecular Function	AMP-activated Protein Kinase Activity CAMP-dependent Protein Kinase Activity Protein Binding ATP Binding Protein Kinase A Regulatory Subunit Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Renal Water Homeostasis Protein Phosphorylation Spermatogenesis Blood Coagulation Male Gonad Development Protein Kinase A Signaling Activation Of Protein Kinase A Activity High-density Lipoprotein Particle Assembly Cellular Response To Glucagon Stimulus	Multicellular Organism Development Spermatogenesis Acrosome Reaction Penetration Of Zona Pellucida Positive Regulation Of Protein Processing Spermatogenesis, Exchange Of Chromosomal Proteins
Pathways		PKA-mediated phosphorylation of CREB PKA-mediated phosphorylation of key metabolic factors Triglyceride catabolism PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Regulation of insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins VEGFA-VEGFR2 Pathway CREB1 phosphorylation through the activation of Adenylate Cyclase CREB1 phosphorylation through the activation of Adenylate Cyclase Degradation of GLI1 by the proteasome Degradation of GLI2 by the proteasome GLI3 is processed to GLI3R by the proteasome Hedgehog 'off' state CD209 (DC-SIGN) signaling MAPK6/MAPK4 signaling RET signaling HDL assembly ROBO receptors bind AKAP5 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Asthma ( 31959851) Bulimia nervosa ( 23568457) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Multiple sclerosis ( 22190364) Type 1 diabetes ( 18978792)
Interacting Genes		5 interacting genes: CDK17 CETP HMGN1 TNP1 TNP2	17 interacting genes: APPBP2 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 MDFI NOTCH2NLA PRKACA PRKACB PRKACG PRKCA
Entrez ID		5568	7142
HPRD ID		01483	01831
Ensembl ID		ENSG00000165059	ENSG00000178279
Uniprot IDs		P22612	Q05952 Q4VB56
PDB IDs
Enriched GO Terms of Interacting Partners?
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