PPP5C and HTR2A

  • Data Source:
  • HPRD (two hybrid)

PPP5C

HTR2A

Description protein phosphatase 5 catalytic subunit 5-hydroxytryptamine receptor 2A
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basophil percentage of white cells ( 27863252)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Hemoglobin ( 32888494)
  • Lymphocyte counts ( 32888494)
  • Monocyte count ( 32888494)
  • Neuroticism ( 29255261)
  • Response to antidepressants in depression ( 29998114)
  • Triglyceride levels ( 32203549)
Interacting Genes 26 interacting genes: APP CDC16 CDC27 CDC37 CDK20 CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L CSNK1D DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A HUWE1 MAP3K5 MAP3K7 MAPT PPP2R1A PPP2R3A VHL 19 interacting genes: ANKS1B ARF1 ARF6 DLG1 DLG4 EIF3F GLUL GNA11 GNAI1 GNAQ JAK2 MAP1A MRPL28 NDUFB10 NME3 NTRK3 PON2 PPP5C RPS6KA3
Entrez ID 5536 3356
HPRD ID 02805 01638
Ensembl ID ENSG00000011485 ENSG00000102468
Uniprot IDs A0A024R0Q7 P53041 P28223
PDB IDs 1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69 4ZVZ 4ZX2 5HPE 5UI1 5WG8 6A93 6A94 6WGT 6WH4 6WHA
Enriched GO Terms of Interacting Partners?
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