GIMAP5 and GJB3

Data Source:
BioGRID (two hybrid)

		GIMAP5	GJB3
Description		GTPase, IMAP family member 5	gap junction protein beta 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Multivesicular Body Membrane	Cytoplasm Gap Junction Connexin Complex Integral Component Of Membrane Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding GTP Binding	Gap Junction Channel Activity Protein Binding
	Biological Process		In Utero Embryonic Development Placenta Development Cell-cell Signaling Spermatogenesis Skin Development Transmembrane Transport Cellular Response To Retinoic Acid
Pathways			Gap junction assembly
Drugs
Diseases			Erythrokeratodermia variabilis Deafness, autosomal dominant Deafness, autosomal recessive
GWAS			Intraocular pressure ( 30591961) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		64 interacting genes: ADGRG3 APP AQP3 AQP6 ARL13B BTNL9 CD33 CD53 CLDN7 CREB3L1 CYB561 CYBRD1 DKK4 EBP EDA EDA2R ELOVL4 EMP1 ERGIC3 EVI2B FAM174A FAM210B FATE1 FCER1G GJA8 GJB3 GORAB GRAMD2B IFNGR2 JAGN1 KASH5 KIR3DL3 LAYN LDLRAD1 LSMEM2 M6PR MGST2 MGST3 MILR1 MS4A14 PDZK1IP1 PTGES RETREG3 RNASEK RNF19B SCN3B SHISAL1 SLC10A1 SLC35C2 SMIM3 SPACA1 STOM STX1A STX2 STX4 SYT1 TM4SF18 TM4SF19 TMEM31 TMX1 TMX2 TNFRSF19 TSPAN18 ZFYVE27	15 interacting genes: BTN2A2 CNST COMT ELAVL1 GIMAP5 IGFBP5 LAT LHFPL5 MFSD11 RPRM SERP1 TJP1 TMEM97 TMUB2 TRARG1
Entrez ID		55340	2707
HPRD ID		16280	04505
Ensembl ID		ENSG00000196329	ENSG00000188910
Uniprot IDs		A0A090N8P9 Q96F15	A0A654ICK0 O75712
PDB IDs
Enriched GO Terms of Interacting Partners?
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