GJB3 and BTN2A2

Data Source:
BioGRID (two hybrid)

		GJB3	BTN2A2
Description		gap junction protein beta 3	butyrophilin subfamily 2 member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Gap Junction Connexin Complex Integral Component Of Membrane Cell Junction Intracellular Membrane-bounded Organelle	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Gap Junction Channel Activity Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	In Utero Embryonic Development Placenta Development Cell-cell Signaling Spermatogenesis Skin Development Transmembrane Transport Cellular Response To Retinoic Acid	Regulation Of Cytokine Production Negative Regulation Of Cytokine Production Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway
Pathways		Gap junction assembly	Butyrophilin (BTN) family interactions
Drugs
Diseases		Erythrokeratodermia variabilis Deafness, autosomal dominant Deafness, autosomal recessive
GWAS		Intraocular pressure ( 30591961) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Neurociticism ( 29500382) Refractive error ( 32231278) Schizophrenia ( 19571809) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		15 interacting genes: BTN2A2 CNST COMT ELAVL1 GIMAP5 IGFBP5 LAT LHFPL5 MFSD11 RPRM SERP1 TJP1 TMEM97 TMUB2 TRARG1	42 interacting genes: AQP6 BIK CD53 CD79A CISD2 CREB3 EBP ELOVL4 EMP1 ERGIC3 EVI2B FAM209A FATE1 FFAR2 GJB3 GPR42 GPRC5D GPX8 HSD3B7 KIR2DL3 LHFPL5 LMNA MRM3 MUC1 PEX12 PSMA3 SEC11C SLC10A6 SLC14A1 SLC16A2 SLC1A3 SLC30A4 SLC39A2 SPNS3 STX1A SYT1 TMEM14B TMEM179B TMEM237 TMEM31 TMEM52B TMX2
Entrez ID		2707	10385
HPRD ID		04505	12545
Ensembl ID		ENSG00000188910	ENSG00000124508
Uniprot IDs		A0A654ICK0 O75712	A0A024R038 Q8WVV5
PDB IDs
Enriched GO Terms of Interacting Partners?
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