UBXN7 and TRIM62

Data Source:
BioGRID (two hybrid)

		UBXN7	TRIM62
Description		UBX domain protein 7	tripartite motif containing 62
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Body VCP-NPL4-UFD1 AAA ATPase Complex	Cytoplasm Cytosol
	Molecular Function	Protein Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Post-translational Protein Modification	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell
Pathways		Neddylation	Interferon gamma signaling
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) IgM levels ( 28628107)	Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		24 interacting genes: APP CLEC19A CRX CYSRT1 DAZAP2 FAM168A MAP3K1 MEOX1 MUL1 NEDD8 NFYC PAX5 PAX6 REL SMURF1 TRAF6 TRIM39 TRIM62 TRIM8 UBC UBQLN1 UBQLN2 VCP ZNRF1	19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25
Entrez ID		26043	55223
HPRD ID		19396	07697
Ensembl ID		ENSG00000163960	ENSG00000116525
Uniprot IDs		O94888	Q9BVG3
PDB IDs		1WJ4 2DAL 2DLX 5X3P 5X4L
Enriched GO Terms of Interacting Partners?
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