MRM3 and GAD2

Data Source:
BioGRID (two hybrid)

		MRM3	GAD2
Description		mitochondrial rRNA methyltransferase 3	glutamate decarboxylase 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Golgi Membrane Cytosol Plasma Membrane Axon Synaptic Vesicle Membrane Anchored Component Of Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding
	Biological Process	RRNA 2'-O-methylation	Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Neurotransmitter Secretion Neurotransmitter Biosynthetic Process Response To Drug
Pathways		rRNA modification in the mitochondrion	GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs			Pyridoxal phosphate Glutamic acid
Diseases
GWAS			Lean body mass ( 28552196)
Interacting Genes		14 interacting genes: AIG1 APP BTN2A2 C4orf3 FBXO7 FHL3 GAD2 GALNT2 JAGN1 MIP SCARF1 TNF UBIAD1 ZFPL1	45 interacting genes: ABHD5 AGTRAP APOC2 APOC4 ARL13B ARL6IP1 ARMC12 BSND CACNG1 CMTM5 CPLX4 CYB561D1 DERL1 DERL3 DGAT2L6 DMKN F10 FADS6 FAM114A2 FAM163A GAD1 HIGD1C LIME1 MAL2 MEST MRM3 PBX3 PLIN3 PRKACA PRKCE RDH10 RHEX RPRM SCAMP1 SDR16C5 SEC22A SMPD2 SPG21 SYCE2 SYNGR3 TMEM120B TMEM128 TMEM159 TNFRSF10D TSPAN33
Entrez ID		55178	2572
HPRD ID		15266	11817
Ensembl ID		ENSG00000171861	ENSG00000136750
Uniprot IDs		Q9HC36	Q05329 Q5VZ30
PDB IDs			1ES0 2OKK
Enriched GO Terms of Interacting Partners?
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