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CEP55 and TP53BP2
Data Source:
BioGRID
(two hybrid)
CEP55
TP53BP2
Description
centrosomal protein 55
tumor protein p53 binding protein 2
Image
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Centriole
Plasma Membrane
Membrane
Midbody
Cleavage Furrow
Centriolar Satellite
Intercellular Bridge
Flemming Body
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cell Junction
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Identical Protein Binding
P53 Binding
Protein Binding
SH3 Domain Binding
Identical Protein Binding
NF-kappaB Binding
Biological Process
Mitotic Cytokinesis
Nucleus Organization
Mitotic Metaphase Plate Congression
Multicellular Organism Development
Regulation Of Phosphatidylinositol 3-kinase Signaling
Establishment Of Protein Localization
Midbody Abscission
Cranial Skeletal System Development
Cell Cycle
Signal Transduction
Regulation Of Apoptotic Process
Negative Regulation Of Cell Cycle
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Positive Regulation Of Execution Phase Of Apoptosis
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Neuron Death
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Activation of PUMA and translocation to mitochondria
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
TP53 Regulates Transcription of Death Receptors and Ligands
Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS
High density lipoprotein cholesterol levels (
30498476
)
Metabolite levels (
23823483
)
Triptolide cytotoxicity (
26121980
)
Interacting Genes
77 interacting genes:
AKAP9
ANXA11
ARHGEF15
C1orf109
C1orf216
CBY2
CCBE1
CCDC120
CCHCR1
CDC37
CDC45
CDK1
CDSN
CEP57L1
COL8A1
DTNB
ECSIT
EIF1AD
ENKD1
FAM161B
FAM90A1
FBF1
FXR2
GOLGA2
GOLGA8DP
HAUS1
HGS
HSF2BP
KANK2
KIFC3
LGALS4
LRRC23
MAPK1
MAPK1IP1L
MFAP1
MIA3
MORF4L2
NDEL1
NOS3
NTAQ1
PCNT
PDCD6IP
PEF1
PIN1
PLEKHG6
PLK1
POLM
POM121
PPP1R16B
PSEN2
PSMC2
PTPN23
PWWP3A
RAB3D
RBM14
RBM17
RBM22
RCOR3
RNF32
SDCBP
SNRPB
SNW1
SS18L1
SUPT5H
TCL1A
TEAD4
TEX11
TEX14
TFG
TP53BP2
TSG101
UBC
VPS37C
VPS37D
WASHC1
WASHC3
ZNF48
122 interacting genes:
ADAMTS12
APP
APPL1
ARHGEF6
ATPAF2
ATXN7
AXIN1
BAG3
BAIAP2
BCAS2
BCL2
BCL2L1
CCDC13
CCDC57
CCDC85A
CCDC92
CDC5L
CEP55
CEP95
CGN
CRK
CSNK2B
CWF19L2
DCUN1D1
DDX6
DIRAS1
EEF1A1
EFHC1
ELOA
GCC1
GEM
GFAP
GOLGA1
GPS2
GRB2
H2BC4
H2BC9
HHEX
HIF1AN
HNRNPUL1
HSF2BP
INSYN2A
IQUB
KDM1A
KIF5A
LHX4
LMNB1
LMNB2
LMO4
MAGI1
MAPK8IP2
MOS
MRPL20
MTMR14
MTURN
NAE1
NDC80
NEDD4
NFKB1
NHSL2
NUTM1
OTUB2
PHF1
PIBF1
PLEKHF2
PLEKHN1
PLK1
POLR2L
PPHLN1
PPP1CA
PPP1CB
PPP1CC
PRAM1
PRKAB2
PRPF31
PTN
RALBP1
RASAL3
RASSF10
RASSF8
RELA
RGMA
RXRB
SCNM1
SETD5
SH3KBP1
SH3RF1
SHTN1
SIAH1
SIAH2
SUMO2
SUMO3
TANK
TBC1D22B
TCL1A
TP53
TRAF4
TROAP
TSGA10
TXLNA
TYK2
UBASH3A
UBASH3B
UBE3A
UBTD1
UNC119
USP4
UTP14A
WWP1
WWP2
YAP1
YES1
YOD1
YWHAG
YWHAQ
ZBTB4
ZFP91
ZGPAT
ZNF26
ZNF438
ZNF552
ZNF575
Entrez ID
55165
7159
HPRD ID
12569
11803
Ensembl ID
ENSG00000138180
ENSG00000143514
Uniprot IDs
Q53EZ4
Q13625
PDB IDs
3E1R
3WUT
3WUU
3WUV
1YCS
2UWQ
4A63
4IRV
6GHM
6HKP
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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