CDCA8 and SGO2

Data Source:
BioGRID (two hybrid)

		CDCA8	SGO2
Description		cell division cycle associated 8	shugoshin 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body Mitotic Cohesin Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division	Mitotic Sister Chromatid Segregation Homologous Chromosome Segregation Meiotic Sister Chromatid Cohesion Cell Division Meiotic Sister Chromatid Cohesion, Centromeric
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		26 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277	6 interacting genes: CDCA8 PPP2CA PPP2R1A PPP2R1B SET SLAIN2
Entrez ID		55143	151246
HPRD ID		13017	11555
Ensembl ID		ENSG00000134690	ENSG00000163535
Uniprot IDs		Q53HL2	B7Z7S9 Q562F6
PDB IDs		2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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