SGO2 and CDCA8

Data Source:
BioGRID (two hybrid)

		SGO2	CDCA8
Description		shugoshin 2	cell division cycle associated 8
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body Mitotic Cohesin Complex	Chromosome, Centromeric Region Nucleoplasm Nucleolus Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Homologous Chromosome Segregation Meiotic Sister Chromatid Cohesion Cell Division Meiotic Sister Chromatid Cohesion, Centromeric	Mitotic Sister Chromatid Segregation Mitotic Metaphase Plate Congression Chromosome Organization Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		6 interacting genes: CDCA8 PPP2CA PPP2R1A PPP2R1B SET SLAIN2	26 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277
Entrez ID		151246	55143
HPRD ID		11555	13017
Ensembl ID		ENSG00000163535	ENSG00000134690
Uniprot IDs		B7Z7S9 Q562F6	Q53HL2
PDB IDs			2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH
Enriched GO Terms of Interacting Partners?
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