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NTAQ1 and PRMT5
Data Source:
BioGRID
(two hybrid)
NTAQ1
PRMT5
Description
N-terminal glutamine amidase 1
protein arginine methyltransferase 5
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Methylosome
Histone Methyltransferase Complex
Molecular Function
Protein Binding
Protein-N-terminal Asparagine Amidohydrolase Activity
Protein-N-terminal Glutamine Amidohydrolase Activity
P53 Binding
Transcription Corepressor Activity
Protein Binding
Methyltransferase Activity
Methyl-CpG Binding
Histone-arginine N-methyltransferase Activity
Protein-arginine N-methyltransferase Activity
Protein-arginine Omega-N Symmetric Methyltransferase Activity
Identical Protein Binding
Ribonucleoprotein Complex Binding
Histone Methyltransferase Activity (H4-R3 Specific)
Protein Heterodimerization Activity
E-box Binding
Biological Process
Cellular Protein Modification Process
Spliceosomal SnRNP Assembly
DNA-templated Transcription, Termination
Regulation Of Transcription, DNA-templated
Regulation Of Mitotic Nuclear Division
Peptidyl-arginine Methylation
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Circadian Regulation Of Gene Expression
Histone Arginine Methylation
Peptidyl-arginine N-methylation
Endothelial Cell Activation
Histone H4-R3 Methylation
Regulation Of DNA Methylation
Negative Regulation Of Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Oligodendrocyte Differentiation
Regulation Of ERK1 And ERK2 Cascade
Golgi Ribbon Formation
Liver Regeneration
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Pathways
snRNP Assembly
RMTs methylate histone arginines
Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS
Cortical amyloid beta load (
29860282
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Interacting Genes
380 interacting genes:
AARD
ACD
ACOT13
ACTB
ACTG1
ACTN2
ACY1
ADAMTSL4
AGR2
AGR3
AIMP2
AKIRIN2
AMOT
AMOTL2
AMPD2
ANKRD11
ANKRD36B
AOC1
APIP
ARID4B
ARL6IP1
ASL
ATP6V1G1
BANF2
BCL2L2-PABPN1
BEND5
BIRC7
BLMH
BLOC1S6
BLZF1
BOLA2
BOLA2B
BORCS6
BPIFB3
BTBD1
BTBD2
BTBD6
C1orf50
CAMK2A
CAPN3
CARD9
CASP6
CAVIN4
CBFA2T2
CBS
CBY2
CCDC102B
CCDC115
CCDC152
CCDC184
CCDC197
CCHCR1
CCNB1IP1
CD22
CDA
CDCA8
CDK2AP1
CDKN2AIPNL
CDR2
CENPP
CEP170B
CEP55
CEP70
CEP85
CGGBP1
CHCHD3
CHMP4A
CMTM5
COG6
COIL
CRYAA
CRYAA2
CSNK2B
CT45A1
CTAG1A
CTAG1B
CTBP1
CTH
CUEDC1
CUTC
CYSRT1
DAB1
DCTPP1
DEUP1
DHPS
DNAL4
DNM2
DYNLT1
EDARADD
EGLN3
EIF2B1
EIF4G1
EMILIN3
ENOX2
EP400
EPN3
ETV6
EXOSC8
FAM136A
FAM72A
FAM72D
FKBP6
FTH1
FTL
GADD45GIP1
GAS7
GCSAML
GFAP
GMCL1
GMDS
GNG3
GNMT
GNPDA2
GOLGA2
GOLGA6L9
GPX7
GRAMD4
GSTA4
GSTO2
GTF2H2C
H2AP
HAUS8
HBQ1
HBZ
HEATR5A
HGD
HIGD1C
HMG20A
HOMER3
HOXB6
HPRT1
HSD17B14
HSF2BP
HSPE1
HUS1
IKZF3
IL16
IL31
INCA1
ISCA2
ITGB3BP
JAKMIP2
JUP
KASH5
KATNBL1
KCNH1
KCTD1
KCTD10
KCTD13
KCTD15
KCTD21
KCTD4
KCTD6
KCTD7
KCTD9
KEAP1
KIF21B
KLHL12
KLHL2
KLHL20
KRT27
KRT31
KRTAP10-5
KRTAP10-7
KRTAP19-2
KRTAP19-6
KRTAP3-1
KRTAP3-3
KRTAP4-2
KRTAP5-9
KRTAP6-1
KRTAP9-2
KRTAP9-4
KRTAP9-8
L3MBTL3
LCE1C
LCE1D
LCE1E
LCE1F
LCE2C
LCE5A
LDB2
LENG1
LGALS2
LGALS9B
LIN7B
LMNA
LMO1
LMO2
LMO3
LNX2
LONRF1
LRIF1
LRRC73
LSM12
LSM14B
LZTFL1
LZTS1
LZTS2
MAB21L3
MAD1L1
MAGEA11
MAGEA12
MAGEA2
MAGEA2B
MALSU1
MARCHF10
MATN4
MDFI
MED22
MIF
MIF4GD
MIOS
MIPOL1
MIS18A
MITD1
MOB2
MORN3
MPLKIP
MRFAP1L1
MRPL12
MTHFD2L
MTUS2
MVP
MXRA8
MYD88
N4BP3
NAB2
NADSYN1
NAGK
NCOA5
NDUFAB1
NECAB2
NME1
NPL
NR5A1
NT5C1A
NTAN1
NUDT14
NUDT16L1
NUDT21
OOEP
PAK5
PCBD1
PFDN5
PGPEP1
PIH1D2
PLA2G10
PLCD1
PLEKHB2
PLEKHJ1
PNMA1
PNMA2
PNMA5
POLR2J
POMC
PPCDC
PPM1K
PPP1R27
PRKAR1B
PRMT1
PRMT5
PRPS2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR23B
PRTFDC1
PSMB5
PSME3
PTS
PYCR3
PYGM
RAB42
RABAC1
RASAL3
RBBP8
RBM20
RBM45
RBM48
RBPMS
RD3
REEP6
RHOQ
RILPL1
RNF138
RNF4
ROPN1
RPIA
RUSC1
S100A11
SAP18
SARS2
SAT1
SCARA5
SELENOV
SEPTIN14
SEPTIN3
SFN
SH3GLB2
SIAH1
SIKE1
SIVA1
SLAIN1
SLC15A2
SLPI
SMAP1
SMN1
SNAP29
SNRPD3
SPANXB1
SPATA32
SPDYE4
SPINDOC
SPRYD7
SSNA1
SSX2IP
STH
STMN2
STN1
STX11
SYCE1L
SYNGAP1
TAX1BP1
TBX15
TCL1A
TCP10L
TEKT1
TEPSIN
THAP1
THAP6
THAP7
THG1L
TICAM2
TIFA
TLE5
TMEM239
TNFAIP1
TNIP3
TNR
TOLLIP
TRAF1
TRAF3
TRAF5
TRIM23
TRIM27
TRIM32
TRIM5
TRIM54
TRIM69
TRIM73
TRIM9
TRIP13
TSC22D1
TSN
TSNAX
UBR1
UBR2
UFC1
UNKL
VAC14
VCP
VDR
VPS37C
VXN
XIAP
ZBED1
ZBTB8A
ZBTB8B
ZC2HC1C
ZCCHC17
ZNF165
ZNF341
ZNF436
ZNF511
ZNF618
ZSCAN16
ZSCAN32
91 interacting genes:
ARGLU1
C1orf109
CACNB2
CALU
CAPN1
CDC37
CDK19
CDK8
CDYL2
CLK1
CLK3
CLNS1A
CTDP1
DIO3
DNMT3A
DUSP14
EIF4A3
ELOA
EPHB6
EZH2
FAM76B
GAS8
GLI1
GRHL3
GTPBP2
H2AC20
H2AC4
H3-4
H3-5
H3C1
H4-16
H4C1
HOXC4
ILF3
ING5
JAK1
JAK2
JAK3
KANK2
LDHAL6B
LENG8
LNX1
LUC7L
MAGEB2
MBP
MCRS1
MEF2D
MYOD1
MYOG
NCL
NELFCD
NTAQ1
NUDCD2
OLA1
PDGFRA
PHYHIP
POLR2A
PRPF38A
RBM23
RSRP1
SF3A3
SIN3A
SLU7
SMARCA2
SMARCB1
SMARCC1
SMARCE1
SNRNP70
SNRPB
SNRPD1
SNRPD3
SPAG8
SREBF1
SSTR1
STUB1
SUPT5H
TRIB3
TRIM54
TYK2
UBE3A
WDR5
WDR77
YWHAG
YWHAQ
YWHAZ
ZDHHC17
ZMYND19
ZNF2
ZNF224
ZNF436
ZUP1
Entrez ID
55093
10419
HPRD ID
07653
04955
Ensembl ID
ENSG00000156795
ENSG00000100462
Uniprot IDs
A0A3B3ITD7
A0A3B3ITI2
E5RHC2
Q96HA8
B4DV00
O14744
PDB IDs
3C9Q
4W79
6KGJ
4GQB
4X60
4X61
4X63
5C9Z
5EMJ
5EMK
5EML
5EMM
5FA5
6CKC
6K1S
6RLL
6RLQ
6UXX
6UXY
6V0N
6V0O
Enriched GO Terms of Interacting Partners
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