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NTAQ1 and SFN
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NTAQ1
SFN
Description
N-terminal glutamine amidase 1
stratifin
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Extracellular Space
Nucleus
Mitochondrion
Cytosol
Extracellular Exosome
Molecular Function
Protein Binding
Protein-N-terminal Asparagine Amidohydrolase Activity
Protein-N-terminal Glutamine Amidohydrolase Activity
Protein Binding
Protein Kinase C Inhibitor Activity
Protein Kinase Binding
Identical Protein Binding
Cadherin Binding
Phosphoprotein Binding
Biological Process
Cellular Protein Modification Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Release Of Cytochrome C From Mitochondria
Keratinocyte Development
Negative Regulation Of Protein Kinase Activity
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Epidermal Cell Division
Negative Regulation Of Keratinocyte Proliferation
Positive Regulation Of Cell Growth
Keratinization
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Epidermal Cell Differentiation
Positive Regulation Of Protein Export From Nucleus
Membrane Organization
Establishment Of Skin Barrier
Negative Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
Drugs
Diseases
GWAS
Basophil percentage of granulocytes (
27863252
)
Basophil percentage of white cells (
27863252
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Eosinophil percentage of white cells (
32888494
)
Neutrophil percentage of granulocytes (
27863252
)
Interacting Genes
380 interacting genes:
AARD
ACD
ACOT13
ACTB
ACTG1
ACTN2
ACY1
ADAMTSL4
AGR2
AGR3
AIMP2
AKIRIN2
AMOT
AMOTL2
AMPD2
ANKRD11
ANKRD36B
AOC1
APIP
ARID4B
ARL6IP1
ASL
ATP6V1G1
BANF2
BCL2L2-PABPN1
BEND5
BIRC7
BLMH
BLOC1S6
BLZF1
BOLA2
BOLA2B
BORCS6
BPIFB3
BTBD1
BTBD2
BTBD6
C1orf50
CAMK2A
CAPN3
CARD9
CASP6
CAVIN4
CBFA2T2
CBS
CBY2
CCDC102B
CCDC115
CCDC152
CCDC184
CCDC197
CCHCR1
CCNB1IP1
CD22
CDA
CDCA8
CDK2AP1
CDKN2AIPNL
CDR2
CENPP
CEP170B
CEP55
CEP70
CEP85
CGGBP1
CHCHD3
CHMP4A
CMTM5
COG6
COIL
CRYAA
CRYAA2
CSNK2B
CT45A1
CTAG1A
CTAG1B
CTBP1
CTH
CUEDC1
CUTC
CYSRT1
DAB1
DCTPP1
DEUP1
DHPS
DNAL4
DNM2
DYNLT1
EDARADD
EGLN3
EIF2B1
EIF4G1
EMILIN3
ENOX2
EP400
EPN3
ETV6
EXOSC8
FAM136A
FAM72A
FAM72D
FKBP6
FTH1
FTL
GADD45GIP1
GAS7
GCSAML
GFAP
GMCL1
GMDS
GNG3
GNMT
GNPDA2
GOLGA2
GOLGA6L9
GPX7
GRAMD4
GSTA4
GSTO2
GTF2H2C
H2AP
HAUS8
HBQ1
HBZ
HEATR5A
HGD
HIGD1C
HMG20A
HOMER3
HOXB6
HPRT1
HSD17B14
HSF2BP
HSPE1
HUS1
IKZF3
IL16
IL31
INCA1
ISCA2
ITGB3BP
JAKMIP2
JUP
KASH5
KATNBL1
KCNH1
KCTD1
KCTD10
KCTD13
KCTD15
KCTD21
KCTD4
KCTD6
KCTD7
KCTD9
KEAP1
KIF21B
KLHL12
KLHL2
KLHL20
KRT27
KRT31
KRTAP10-5
KRTAP10-7
KRTAP19-2
KRTAP19-6
KRTAP3-1
KRTAP3-3
KRTAP4-2
KRTAP5-9
KRTAP6-1
KRTAP9-2
KRTAP9-4
KRTAP9-8
L3MBTL3
LCE1C
LCE1D
LCE1E
LCE1F
LCE2C
LCE5A
LDB2
LENG1
LGALS2
LGALS9B
LIN7B
LMNA
LMO1
LMO2
LMO3
LNX2
LONRF1
LRIF1
LRRC73
LSM12
LSM14B
LZTFL1
LZTS1
LZTS2
MAB21L3
MAD1L1
MAGEA11
MAGEA12
MAGEA2
MAGEA2B
MALSU1
MARCHF10
MATN4
MDFI
MED22
MIF
MIF4GD
MIOS
MIPOL1
MIS18A
MITD1
MOB2
MORN3
MPLKIP
MRFAP1L1
MRPL12
MTHFD2L
MTUS2
MVP
MXRA8
MYD88
N4BP3
NAB2
NADSYN1
NAGK
NCOA5
NDUFAB1
NECAB2
NME1
NPL
NR5A1
NT5C1A
NTAN1
NUDT14
NUDT16L1
NUDT21
OOEP
PAK5
PCBD1
PFDN5
PGPEP1
PIH1D2
PLA2G10
PLCD1
PLEKHB2
PLEKHJ1
PNMA1
PNMA2
PNMA5
POLR2J
POMC
PPCDC
PPM1K
PPP1R27
PRKAR1B
PRMT1
PRMT5
PRPS2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR23B
PRTFDC1
PSMB5
PSME3
PTS
PYCR3
PYGM
RAB42
RABAC1
RASAL3
RBBP8
RBM20
RBM45
RBM48
RBPMS
RD3
REEP6
RHOQ
RILPL1
RNF138
RNF4
ROPN1
RPIA
RUSC1
S100A11
SAP18
SARS2
SAT1
SCARA5
SELENOV
SEPTIN14
SEPTIN3
SFN
SH3GLB2
SIAH1
SIKE1
SIVA1
SLAIN1
SLC15A2
SLPI
SMAP1
SMN1
SNAP29
SNRPD3
SPANXB1
SPATA32
SPDYE4
SPINDOC
SPRYD7
SSNA1
SSX2IP
STH
STMN2
STN1
STX11
SYCE1L
SYNGAP1
TAX1BP1
TBX15
TCL1A
TCP10L
TEKT1
TEPSIN
THAP1
THAP6
THAP7
THG1L
TICAM2
TIFA
TLE5
TMEM239
TNFAIP1
TNIP3
TNR
TOLLIP
TRAF1
TRAF3
TRAF5
TRIM23
TRIM27
TRIM32
TRIM5
TRIM54
TRIM69
TRIM73
TRIM9
TRIP13
TSC22D1
TSN
TSNAX
UBR1
UBR2
UFC1
UNKL
VAC14
VCP
VDR
VPS37C
VXN
XIAP
ZBED1
ZBTB8A
ZBTB8B
ZC2HC1C
ZCCHC17
ZNF165
ZNF341
ZNF436
ZNF511
ZNF618
ZSCAN16
ZSCAN32
56 interacting genes:
ABL1
ARAF
BAD
BAX
BCR
BRAF
CCAR1
CCDC102B
CCDC125
CCNH
CDC25B
CDK1
CHST1
COP1
DUXAP9
EEF1A1
EGFR
EIF2S1
EIF4B
EXO1
FAM189A2
FAM53C
FAM9B
FOXO1
FOXO4
GPRIN2
HDAC5
HNRNPD
ING1
KCNK15
KCNK3
KCNK9
KIAA0408
LNX2
LONRF1
MAGEA1
MAP3K5
MARK3
MDM4
MKRN3
MST1R
NR3C1
NTAQ1
PAX9
PLEKHF2
PLK4
RAB3IP
RFFL
SAMSN1
TBL3
TP53
TRIM25
TSC2
YWHAG
ZC2HC1C
ZFP36
Entrez ID
55093
2810
HPRD ID
07653
03185
Ensembl ID
ENSG00000156795
ENSG00000175793
Uniprot IDs
A0A3B3ITD7
A0A3B3ITI2
E5RHC2
Q96HA8
P31947
PDB IDs
3C9Q
4W79
6KGJ
1YWT
1YZ5
3IQJ
3IQU
3IQV
3LW1
3MHR
3O8I
3P1N
3P1O
3P1P
3P1Q
3P1R
3P1S
3SMK
3SML
3SMM
3SMN
3SMO
3SP5
3SPR
3T0L
3T0M
3U9X
3UX0
4DAT
4DAU
4DHM
4DHN
4DHO
4DHP
4DHQ
4DHR
4DHS
4DHT
4DHU
4FL5
4FR3
4IEA
4JC3
4JDD
4QLI
4Y32
4Y3B
4Y5I
5BTV
5HF3
5LTW
5LU1
5LU2
5MHC
5MOC
5MXO
5MY9
5MYC
5N5R
5N5T
5N5W
5N75
5OEG
5OEH
5OK9
5OKF
5OM0
5OMA
6FAU
6FAV
6FAW
6FBB
6FBW
6FBY
6FCP
6FI4
6FI5
6G6X
6G8I
6G8J
6G8K
6G8L
6G8P
6G8Q
6GHP
6HHP
6HKB
6HKF
6HMT
6HMU
6HN2
6NV2
6QDR
6QDS
6QDT
6QDU
6QHL
6QHM
6QIU
6QZR
6QZS
6R5L
6RHC
6RJL
6RJQ
6RJZ
6RK8
6RKI
6RKK
6RKM
6RL3
6RL4
6RL6
6RM5
6RM7
6RP6
6RWH
6RWI
6RWS
6RWU
6RX2
6S39
6S3C
6S40
6S9Q
6SIN
6SIO
6SIP
6SIQ
6SLV
6SLW
6SLX
6TCH
6TJM
6TL3
6TLF
6TLG
6TM7
6TWZ
6W0L
6XWD
6Y1J
6Y3M
6Y3O
6Y3R
6Y3S
6Y3V
6Y40
6Y44
6Y8A
6Y8B
6Y8D
6Y8E
6YOW
6YOX
6YOY
6YP2
6YP3
6YP8
6YPL
6YPY
6YQ2
7AEW
Enriched GO Terms of Interacting Partners
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