MED9 and USP47

Data Source:
HPRD (in vitro)

		MED9	USP47
Description		mediator complex subunit 9	ubiquitin specific peptidase 47
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mediator Complex	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding WD40-repeat Domain Binding Ubiquitinyl Hydrolase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Base-excision Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Protein Phosphopantetheinylation Positive Regulation Of Cell Growth Regulation Of Protein Stability Cellular Response To UV Monoubiquitinated Protein Deubiquitination Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Ub-specific processing proteases
Drugs
Diseases
GWAS		Birth weight ( 31043758) Estimated glomerular filtration rate ( 31152163)	Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		26 interacting genes: APP CBX4 CDK8 MED1 MED11 MED12 MED13 MED14 MED16 MED18 MED19 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 USP47	6 interacting genes: AP4M1 MED29 MED9 PLA2G2A SNCA UBC
Entrez ID		55090	55031
HPRD ID		14383	11668
Ensembl ID		ENSG00000141026	ENSG00000170242
Uniprot IDs		Q9NWA0	Q68D97 Q96K76
PDB IDs
Enriched GO Terms of Interacting Partners?
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