IFT57 and CLTA

Data Source:
BioGRID (affinity chromatography technology)

		IFT57	CLTA
Description		intraflagellar transport 57	clathrin light chain A
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Centrosome Cilium Axoneme Intraciliary Transport Particle B Photoreceptor Connecting Cilium Ciliary Basal Body Dendrite Terminus Ciliary Tip	Spindle Cytosol Plasma Membrane Membrane Clathrin Coat Clathrin Vesicle Coat Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Synaptic Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Endolysosome Membrane Clathrin-coated Endocytic Vesicle Clathrin Complex Presynaptic Endocytic Zone Membrane Postsynaptic Endocytic Zone Cytoplasmic Component
	Molecular Function	DNA Binding Protein Binding	Molecular_function Structural Molecule Activity Protein Binding Clathrin Heavy Chain Binding Peptide Binding Protein-containing Complex Binding GTPase Binding
	Biological Process	Neural Tube Closure Heart Looping Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Regulation Of Apoptotic Process Motile Cilium Assembly Negative Regulation Of Epithelial Cell Proliferation Left/right Pattern Formation Non-motile Cilium Assembly	Intracellular Protein Transport Cell Cycle Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Low-density Lipoprotein Particle Receptor Catabolic Process Low-density Lipoprotein Particle Clearance Clathrin Coat Assembly Cell Division Membrane Organization Clathrin-dependent Endocytosis
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport	Entry of Influenza Virion into Host Cell via Endocytosis Retrograde neurotrophin signalling Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Lysosome Vesicle Biogenesis Recycling pathway of L1 Recycling pathway of L1 WNT5A-dependent internalization of FZD4 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis VLDLR internalisation and degradation LDL clearance
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder ( 31043756) Regular attendance at a religious group ( 29970889)	Bipolar disorder (inflammation and infection response interaction) ( 25781172) Bisphosphonate-associated atypical femoral fracture ( 31006051)
Interacting Genes		8 interacting genes: EXOC5 HIP1 IFT20 SKA2 UBXN10 WASHC1 YAF2 ZDHHC17	8 interacting genes: CLTC EGFR HIP1 HIP1R HSPA8 MAP1LC3B RGS2 SYNJ1
Entrez ID		55081	1211
HPRD ID		09430	00351
Ensembl ID		ENSG00000114446	ENSG00000122705
Uniprot IDs		Q9NWB7	C9J8P9 P09496
PDB IDs			6E5N
Enriched GO Terms of Interacting Partners?
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