VPS37C and TFG

Data Source:
BioGRID (two hybrid, two hybrid)

		VPS37C	TFG
Description		VPS37C subunit of ESCRT-I	trafficking from ER to golgi regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell Extracellular Exosome	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	COPII-mediated vesicle transport
Drugs
Diseases			Non-small cell lung cancer Thyroid cancer
GWAS		Periventricular white matter hyperintensities ( 32517579) Rheumatoid arthritis ( 23143596)	Refractive error ( 32231278)
Interacting Genes		102 interacting genes: AARD ABHD11 ABI2 APP ASCL3 BAG4 BIRC7 C1orf94 CBFA2T3 CEP55 CRX DAZAP2 DCTN3 DDIT3 DYDC1 EYA2 FAM168A FAM168B FCHSD2 FOXI1 FUBP1 GOLGA2 GPS2 GRB2 HAUS1 HELT HGS HNRNPF HNRNPUL1 HYI ILF3 KLF1 KRT27 KRT33B KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP7-1 LAGE3 LASP1 MAPK1IP1L METTL27 NTAQ1 NUP54 NUTM2F P4HA3 PAX9 PDCD6 PDCD6IP PEF1 PKNOX1 PKNOX2 PLA2G10 PLEKHG4 PLSCR1 POLR2J POLR2J3 POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 RAMAC RBPMS RBPMS2 RFX6 RIBC1 RINT1 RPRD1B RUNX1 SH3GL1 SH3RF1 SH3RF2 SORBS2 SORBS3 SPAG8 STAM2 STH TACC3 TFAP2D TFG TFIP11 TIAL1 TLE5 TSC1 TSG101 UBAP2 UBC UFSP1 VPS28 WWOX WWP2 XIAP YTHDF1 ZMAT5 ZMYND12 ZNF34	73 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 C19orf54 CEP126 CEP55 CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PPP1R32 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SEC24A SF3A2 SF3B4 SMUG1 SPG21 STAT5B STH TBX19 TEX37 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34
Entrez ID		55048	10342
HPRD ID		15652	03932
Ensembl ID		ENSG00000167987	ENSG00000114354
Uniprot IDs		A5D8V6	Q05BK6 Q92734
PDB IDs
Enriched GO Terms of Interacting Partners?
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