QRICH1 and CRX

Data Source:
BioGRID (two hybrid, two hybrid)

		QRICH1	CRX
Description		glutamine rich 1	cone-rod homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Chromatin Nucleus RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Biological_process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Nervous System Development Visual Perception Animal Organ Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus
Pathways
Drugs
Diseases			Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) General factor of neuroticism ( 30867560) Inflammatory bowel disease ( 28067908) Refractive error ( 32231278) Resting heart rate ( 27798624) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		53 interacting genes: ACTL9 ARID5A ATF7IP ATXN1 BICRAL C15orf65 C19orf54 CEACAM6 CRX CYSRT1 DNAAF6 FAM166B FHL2 FHL3 FHL5 GMCL1 HIVEP1 HSFY1 HSPB8 KHDC4 KLHDC7B LASP1 LBX1 LHX3 LHX4 LMO3 LMO4 MEOX1 MYH7B NFIX NFYA NLK PAX6 POGZ POU6F2 PRKAR1B PUF60 RBM17 SELENOV SEPHS1 SIAH1 SMAP1 SP2 SRARP TEKT5 TOX4 TRAF1 TRAF2 USP54 YPEL3 ZDHHC17 ZMAT1 ZYX	112 interacting genes: AASDHPPT ABI2 ACBD4 ARIH2 ATG12 ATM ATP6V0D2 ATXN1 ATXN7 BANF1 BANF2 BANP BOD1L2 C19orf25 C1orf109 C1orf50 C1orf56 C9orf72 CA8 CCNC CDKN2C CFAP206 CREBBP CSNK1G2-AS1 CTNNA3 DELE1 EIF5A EP300 FAAP20 FOXH1 GCM2 GLIS2 GUCD1 GYS1 HGS HNF1B IGFN1 IPO13 IRX6 KANK2 KAT2A KLHL32 LARP4 LGALS3 LIMS3 LIMS4 LNX1 LONRF1 M1AP MDFI MLLT6 MYO15B MYOZ1 NEIL2 NFYC NIP7 NPAS2 NR2E3 NRL NTF4 OR6B1 OSGIN1 OSTF1 PDC PICALM PID1 PNMA6A POGZ PPP1R16B PRKAB2 PRKN PRR35 PSMA1 PSMB10 PSMF1 QRICH1 RAX2 RBFOX1 RBPMS RHOXF2 ROR2 SAE1 SDCBP SEC14L4 SFI1 SMAD3 SMAP1 SMAP2 SMUG1 SOX10 SOX14 SOX3 SOX5 SPG21 STK16 SUFU SUOX SZT2 TBX6 TCF7L2 TEX33 TFG TLE5 TLX3 TNS2 UBXN2B UBXN7 VPS37C ZC3H10 ZIC1 ZNF483 ZNF688
Entrez ID		54870	1406
HPRD ID		13372	03748
Ensembl ID		ENSG00000198218	ENSG00000105392
Uniprot IDs		A1L3Z9 Q2TAL8	O43186
PDB IDs
Enriched GO Terms of Interacting Partners?
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