PAQR5 and SGPL1

Data Source:
BioGRID (two hybrid)

		PAQR5	SGPL1
Description		progestin and adipoQ receptor family member 5	sphingosine-1-phosphate lyase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Steroid Binding Protein Binding Signaling Receptor Activity	Protein Binding Sphinganine-1-phosphate Aldolase Activity Carboxy-lyase Activity Pyridoxal Phosphate Binding
	Biological Process	Multicellular Organism Development Oogenesis	Luteinization Vasculogenesis Ameboidal-type Cell Migration Kidney Development Fatty Acid Metabolic Process Ceramide Metabolic Process Spermatogenesis Androgen Metabolic Process Estrogen Metabolic Process Post-embryonic Development Fibroblast Migration Hemopoiesis Sphingolipid Biosynthetic Process Sphingolipid Catabolic Process Leydig Cell Differentiation Regulation Of Multicellular Organism Growth Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis Roof Of Mouth Development Face Morphogenesis Apoptotic Signaling Pathway
Pathways			Sphingolipid de novo biosynthesis
Drugs			Pyridoxal phosphate
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Calcium levels ( 29403010) Diastolic blood pressure ( 27841878) Systolic blood pressure ( 30578418)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Metabolite levels ( 23823483) Microalbuminuria ( 26631737) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		7 interacting genes: ERGIC3 GPX8 IGSF9 IL3RA LMNA SGPL1 SYNE4	35 interacting genes: AQP3 AQP9 BCL2L2 BRICD5 CCL4L2 CLDN19 EFNA5 ERG28 FA2H FAM177A1 FXYD3 HMOX2 IFITM3 MARCHF5 MFSD6 MIP MMD2 PAQR5 PLP2 PLPP4 RNASE10 RTP2 SCAMP5 SLC30A3 SRPK2 STATH STING1 STX4 STX8 TMEM176A TMEM242 TMEM97 TRARG1 TSPAN4 UNC50
Entrez ID		54852	8879
HPRD ID		08475	07224
Ensembl ID		ENSG00000137819	ENSG00000166224
Uniprot IDs		A0A024R607 Q9NXK6	O95470
PDB IDs			4Q6R
Enriched GO Terms of Interacting Partners?
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