TRPM7 and TRPM6

Data Source:
HPRD (in vivo, in vitro)

		TRPM7	TRPM6
Description		transient receptor potential cation channel subfamily M member 7	transient receptor potential cation channel subfamily M member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Brush Border Membrane
	Molecular Function	Actin Binding Cation Channel Activity Calcium Channel Activity ATP Binding Myosin Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Cation Channel Activity Calcium Channel Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Calcium Ion Transport Cellular Magnesium Ion Homeostasis Calcium-dependent Cell-matrix Adhesion Actomyosin Structure Organization Protein Autophosphorylation Protein Tetramerization Necroptotic Process Calcium Ion Transmembrane Transport Divalent Inorganic Cation Homeostasis Cation Transmembrane Transport	Protein Phosphorylation Response To Toxic Substance Protein Tetramerization Calcium Ion Transmembrane Transport Cation Transmembrane Transport
Pathways		TRP channels	TRP channels
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester 1,4-Dithiothreitol
Diseases
GWAS		Calcium levels ( 29403010) Chronic obstructive pulmonary disease ( 30804561) Electrocardiographic traits ( 32602732) Household income (MTAG) ( 31844048) Pulse pressure ( 27841878) QT interval ( 24952745) Systolic blood pressure ( 27841878)	Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Magnesium levels ( 20700443 26058915) Metabolite levels ( 23823483) Pre-treatment viral load in HIV-1 infection ( 31219150) Prepulse inhibition of the startle response ( 31596458) Urinary magnesium-to-creatinine ratio ( 29093028)
Interacting Genes		9 interacting genes: ANXA1 EEF2 H3-4 MBP PLCB1 PLCB2 PLCB3 PLCG1 TRPM6	1 interacting genes: TRPM7
Entrez ID		54822	140803
HPRD ID		10418	06112
Ensembl ID		ENSG00000092439	ENSG00000119121
Uniprot IDs		A0A024R5V1 H0YLN8 Q96QT4	Q9BX84
PDB IDs
Enriched GO Terms of Interacting Partners?
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