TRPM6 and TRPM7

Data Source:
HPRD (in vivo, in vitro)

		TRPM6	TRPM7
Description		transient receptor potential cation channel subfamily M member 6	transient receptor potential cation channel subfamily M member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Brush Border Membrane	Ruffle Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Cation Channel Activity Calcium Channel Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Actin Binding Cation Channel Activity Calcium Channel Activity ATP Binding Myosin Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Protein Phosphorylation Response To Toxic Substance Protein Tetramerization Calcium Ion Transmembrane Transport Cation Transmembrane Transport	Calcium Ion Transport Cellular Magnesium Ion Homeostasis Calcium-dependent Cell-matrix Adhesion Actomyosin Structure Organization Protein Autophosphorylation Protein Tetramerization Necroptotic Process Calcium Ion Transmembrane Transport Divalent Inorganic Cation Homeostasis Cation Transmembrane Transport
Pathways		TRP channels	TRP channels
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester 1,4-Dithiothreitol
Diseases
GWAS		Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Magnesium levels ( 20700443 26058915) Metabolite levels ( 23823483) Pre-treatment viral load in HIV-1 infection ( 31219150) Prepulse inhibition of the startle response ( 31596458) Urinary magnesium-to-creatinine ratio ( 29093028)	Calcium levels ( 29403010) Chronic obstructive pulmonary disease ( 30804561) Electrocardiographic traits ( 32602732) Household income (MTAG) ( 31844048) Pulse pressure ( 27841878) QT interval ( 24952745) Systolic blood pressure ( 27841878)
Interacting Genes		1 interacting genes: TRPM7	9 interacting genes: ANXA1 EEF2 H3-4 MBP PLCB1 PLCB2 PLCB3 PLCG1 TRPM6
Entrez ID		140803	54822
HPRD ID		06112	10418
Ensembl ID		ENSG00000119121	ENSG00000092439
Uniprot IDs		Q9BX84	A0A024R5V1 H0YLN8 Q96QT4
PDB IDs
Enriched GO Terms of Interacting Partners?
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