HAUS6 and HAUS8

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		HAUS6	HAUS8
Description		HAUS augmin like complex subunit 6	HAUS augmin like complex subunit 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Nuclear Speck Centriolar Satellite HAUS Complex Mitotic Spindle Microtubule	Spindle Pole Cytoplasm Centrosome Cytosol Nuclear Microtubule HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Molecular_function Protein Binding Microtubule Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Platelet count ( 32888494) Prostate cancer ( 29892016) Prostate cancer (early onset) ( 29892016) Pulse pressure ( 30224653 30578418) Type 2 diabetes ( 30297969)	Mean corpuscular hemoglobin concentration ( 32888494) Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758)
Interacting Genes		3 interacting genes: APP HAUS8 KDM1A	14 interacting genes: APP C1orf216 CCHCR1 DEUP1 HAUS5 HAUS6 HSPB1 NME7 NRDE2 NTAQ1 NUP54 TXN2 USHBP1 ZG16B
Entrez ID		54801	93323
HPRD ID		13302	11318
Ensembl ID		ENSG00000147874	ENSG00000131351
Uniprot IDs		Q7Z4H7	Q9BT25
PDB IDs
Enriched GO Terms of Interacting Partners?
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