HAUS8 and NRDE2

Data Source:
BioGRID (two hybrid)

		HAUS8	NRDE2
Description		HAUS augmin like complex subunit 8	NRDE-2, necessary for RNA interference, domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Cytosol Nuclear Microtubule HAUS Complex Mitotic Spindle Microtubule	Nucleoplasm Nucleolus Nuclear Speck
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Molecular_function Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking	RNA Interference Heterochromatin Assembly By Small RNA Positive Regulation Of RNA Export From Nucleus Negative Regulation Of RNA Catabolic Process
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 32888494) Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758)	Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		14 interacting genes: APP C1orf216 CCHCR1 DEUP1 HAUS5 HAUS6 HSPB1 NME7 NRDE2 NTAQ1 NUP54 TXN2 USHBP1 ZG16B	11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28
Entrez ID		93323	55051
HPRD ID		11318	12625
Ensembl ID		ENSG00000131351	ENSG00000119720
Uniprot IDs		Q9BT25	Q9H7Z3
PDB IDs			6IEH
Enriched GO Terms of Interacting Partners?
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