NLGN3 and TXNIP

Data Source:
BioGRID (two hybrid)

		NLGN3	TXNIP
Description		neuroligin 3	thioredoxin interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endocytic Vesicle Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse Integral Component Of Postsynaptic Membrane	Nucleus Cytoplasm Mitochondrial Intermembrane Space Cytosol
	Molecular Function	Protein Binding Signaling Receptor Activity Neurexin Family Protein Binding Cell Adhesion Molecule Binding Scaffold Protein Binding	Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Receptor-mediated Endocytosis Neuron Cell-cell Adhesion Chemical Synaptic Transmission Synapse Assembly Learning Adult Behavior Social Behavior Synaptic Vesicle Endocytosis Axon Extension Modulation Of Chemical Synaptic Transmission Synapse Organization Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Rhythmic Synaptic Transmission Inhibitory Postsynaptic Potential Vocalization Behavior Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of AMPA Receptor Activity	Negative Regulation Of Transcription By RNA Polymerase II Protein Import Into Nucleus Cell Cycle Response To Mechanical Stimulus Response To Glucose Protein Transport Keratinocyte Differentiation Response To Estradiol Response To Progesterone Regulation Of Cell Population Proliferation Response To Drug Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Platelet-derived Growth Factor Receptor Signaling Pathway Response To Calcium Ion Negative Regulation Of Cell Division Cellular Response To Tumor Cell
Pathways		Neurexins and neuroligins Neurexins and neuroligins	The NLRP3 inflammasome The NLRP3 inflammasome Regulation of FOXO transcriptional activity by acetylation Purinergic signaling in leishmaniasis infection Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Prostate cancer ( 25217961)
Interacting Genes		55 interacting genes: ALPP AP2A2 ATF4 C1orf122 C1QA CCAR2 CGB3 CTSD DLG2 DLG3 DLG4 DPEP2 EBPL EFS FANCG FBLN1 FHOD1 FKBP1A FLNA GDF15 GUK1 HID1 ITPRIP LGALS1 MAN2C1 MAP1S MEOX2 MIEN1 NFATC4 NRDC NRXN1 NRXN2 NRXN3 OAZ1 OR1F12 PKIB PLB1 PLCB4 PRDX2 PSAP PSG1 PSG11 PSG3 PSG4 PSG5 QARS1 SPAG5 SPINT1 SSR4 TNNT3 TRIM33 TXNIP UBQLN1 UBXN6 UQCRC1	20 interacting genes: DDIT4 ECD FHL1 HDAC1 HDAC3 HSPB2 ITCH KPNA2 MAPK1 NLGN3 PRKAA1 PTPN11 SCEL SMURF2 TRAF6 TXN TXNRD1 UBR5 ZBTB16 ZBTB32
Entrez ID		54413	10628
HPRD ID		02275	05964
Ensembl ID		ENSG00000196338	ENSG00000265972
Uniprot IDs		B7Z3P8 Q4G160 Q6MZK0 Q9NZ94 X5D2P6 X5D7L6 X5DNV3	Q9H3M7
PDB IDs			4GEI 4GEJ 4GFX 4LL1 4LL4 4ROF 4ROJ 5CQ2 5DF6 5DWS 5DZD
Enriched GO Terms of Interacting Partners?
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