TXNIP and SCEL

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo)

		TXNIP	SCEL
Description		thioredoxin interacting protein	sciellin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrial Intermembrane Space Cytosol	Cornified Envelope Cytoplasm Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Import Into Nucleus Cell Cycle Response To Mechanical Stimulus Response To Glucose Protein Transport Keratinocyte Differentiation Response To Estradiol Response To Progesterone Regulation Of Cell Population Proliferation Response To Drug Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Platelet-derived Growth Factor Receptor Signaling Pathway Response To Calcium Ion Negative Regulation Of Cell Division Cellular Response To Tumor Cell	Epidermis Development Response To Mechanical Stimulus Embryo Development Ending In Birth Or Egg Hatching Keratinocyte Differentiation Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		The NLRP3 inflammasome The NLRP3 inflammasome Regulation of FOXO transcriptional activity by acetylation Purinergic signaling in leishmaniasis infection Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS			Chronotype ( 30696823) Craniofacial microsomia ( 26853712) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Morning person ( 30696823)
Interacting Genes		20 interacting genes: DDIT4 ECD FHL1 HDAC1 HDAC3 HSPB2 ITCH KPNA2 MAPK1 NLGN3 PRKAA1 PTPN11 SCEL SMURF2 TRAF6 TXN TXNRD1 UBR5 ZBTB16 ZBTB32	13 interacting genes: APP DAPK1 FXR2 GOLGA2 KIFC3 LRRK1 LRRK2 MTUS2 NMI PTPRD TSC22D2 TSGA10 TXNIP
Entrez ID		10628	8796
HPRD ID		05964	09161
Ensembl ID		ENSG00000265972	ENSG00000136155
Uniprot IDs		Q9H3M7	O95171
PDB IDs		4GEI 4GEJ 4GFX 4LL1 4LL4 4ROF 4ROJ 5CQ2 5DF6 5DWS 5DZD
Enriched GO Terms of Interacting Partners?
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