ERRFI1 and PPIA

Data Source:
BioGRID (two hybrid)

		ERRFI1	PPIA
Description		ERBB receptor feedback inhibitor 1	peptidylprolyl isomerase A
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Extracellular Region Extracellular Space Nucleus Cytoplasm Cytosol Focal Adhesion Membrane Vesicle Protein-containing Complex Secretory Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding Protein Kinase Binding Small GTPase Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Integrin Binding Protein Binding Cyclosporin A Binding Virion Binding Unfolded Protein Binding Heparan Sulfate Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Interleukin-1 Beta Production Cellular Response To Insulin Stimulus Negative Regulation Of Collagen Biosynthetic Process Cellular Response To Platelet-derived Growth Factor Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of GTPase Activity Skin Morphogenesis Regulation Of Keratinocyte Differentiation Lung Alveolus Development Lung Vasculature Development Lung Epithelium Development Regulation Of Type B Pancreatic Cell Proliferation Negative Regulation Of ERK1 And ERK2 Cascade Cellular Response To Epidermal Growth Factor Stimulus Cellular Hyperosmotic Response Cellular Response To Dexamethasone Stimulus Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress	Activation Of MAPK Activity Protein Peptidyl-prolyl Isomerization Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation RNA-dependent DNA Biosynthetic Process Protein Folding Negative Regulation Of Protein Kinase Activity Apoptotic Process Viral Life Cycle Uncoating Of Virus Fusion Of Virus Membrane With Host Plasma Membrane Virion Assembly Viral Release From Host Cell Platelet Activation Neutrophil Chemotaxis Leukocyte Chemotaxis Activation Of Protein Kinase B Activity Negative Regulation Of Stress-activated MAPK Cascade Lipid Droplet Organization Cellular Response To Oxidative Stress Positive Regulation Of Protein Dephosphorylation Interleukin-12-mediated Signaling Pathway Endothelial Cell Activation Neutrophil Degranulation Regulation Of Viral Genome Replication Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Leukocyte Migration Positive Regulation Of NF-kappaB Transcription Factor Activity Cell Adhesion Molecule Production Negative Regulation Of Protein K48-linked Ubiquitination Platelet Aggregation Establishment Of Integrated Proviral Latency Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Viral Life Cycle Regulation Of Apoptotic Signaling Pathway
Pathways			Platelet degranulation Uncoating of the HIV Virion Budding and maturation of HIV virion Integration of provirus Early Phase of HIV Life Cycle Minus-strand DNA synthesis Plus-strand DNA synthesis Binding and entry of HIV virion Assembly Of The HIV Virion APOBEC3G mediated resistance to HIV-1 infection Calcineurin activates NFAT Basigin interactions Neutrophil degranulation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Cyclosporine Proline (3r)-1-Acetyl-3-Methylpiperidine Ethyl Oxo(Piperidin-1-Yl)Acetate Sanglifehrin A Copper Artenimol
Diseases
GWAS		Crohn's disease ( 28067908) Hair shape ( 29220522) Inflammatory bowel disease ( 28067908) Ischemic stroke ( 24262325) Morning person ( 30696823) Response to antidepressants and depression ( 27622933) Strep throat ( 28928442) Ulcerative colitis ( 28067908)	Mean reticulocyte volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		60 interacting genes: ACBD3 ADAM5 AGPAT4-IT1 AOX1 ARRDC5 ATM AURKA BAG4 BCAR3 CASP8 CDC42 CIAO2B COPS5 CRHBP DCTN6 EFEMP1 EGFR ERBB2 FGFR2 FGFR4 FYN GAS1 GNPDA2 GRB2 GTF2H2 HYDIN IL2RG MFSD5 MMP26 NEDD4 NEU1 NPC2 OSTF1 PALB2 PAPSS1 PCCA PCNA PDCD2 PHYHIPL PLEKHA3 PPIA PPM1D PSMA7 PSMB6 RAB18 RB1CC1 RUBCNL SH3YL1 SLC7A13 SMIM30 SRC TC2N TIMP4 TM2D3 TMEM165 TMEM59 WDR61 WEE1 YWHAB ZPBP	27 interacting genes: APP BSG CD99 ERCC6 ERRFI1 G3BP1 ITK JAK2 LIG4 LNX1 N4BP2L2 NOTCH3 PAXIP1 PRLR PRR13 PRSS23 PTPRN RB1 S100A8 SRPK1 SRPK2 SUPT5H TCF4 TERT USP4 WBP4 YY1
Entrez ID		54206	5478
HPRD ID		09218	00457
Ensembl ID		ENSG00000116285	ENSG00000196262
Uniprot IDs		B3KTV8 I6S2Y9 Q9UJM3	P62937 V9HWF5
PDB IDs		2RF9 2RFD 2RFE 4I21 4R3P 4R3R 4ZJV	1AK4 1AWQ 1AWR 1AWS 1AWT 1AWU 1AWV 1BCK 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1FGL 1M63 1M9C 1M9D 1M9E 1M9F 1M9X 1M9Y 1MF8 1MIK 1NMK 1OCA 1RMH 1VBS 1VBT 1W8L 1W8M 1W8V 1YND 1ZKF 2ALF 2CPL 2CYH 2MS4 2MZU 2N0T 2RMA 2RMB 2X25 2X2A 2X2C 2X2D 2XGY 3CYH 3CYS 3K0M 3K0N 3K0O 3K0P 3K0Q 3K0R 3ODI 3ODL 3RDD 4CYH 4IPZ 4N1M 4N1N 4N1O 4N1P 4N1Q 4N1R 4N1S 4YUG 4YUH 4YUI 4YUJ 4YUK 4YUL 4YUM 4YUN 4YUO 4YUP 5CYH 5F66 5FJB 5KUL 5KUN 5KUO 5KUQ 5KUR 5KUS 5KUU 5KUV 5KUW 5KUZ 5KV0 5KV1 5KV2 5KV3 5KV4 5KV5 5KV6 5KV7 5LUD 5NOQ 5NOR 5NOS 5NOT 5NOU 5NOV 5NOW 5NOX 5NOY 5NOZ 5T9U 5T9W 5T9Z 5TA2 5TA4 5WC7 6BTA 6GJI 6GJJ 6GJL 6GJM 6GJN 6GJP 6GJR 6GJY 6GS6 6I42 6U5C 6U5D 6U5E 6U5G 6X3R 6X3Y 6X4M 6X4N 6X4O 6X4P 6X4Q 6Y9V 6Y9W 6Y9X 6Y9Y 6Y9Z 6ZDJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?