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POLE3 and CHRAC1
Data Source:
HPRD
(in vivo)
POLE3
CHRAC1
Description
DNA polymerase epsilon 3, accessory subunit
chromatin accessibility complex subunit 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Ada2/Gcn5/Ada3 Transcription Activator Complex
Epsilon DNA Polymerase Complex
CHRAC
Nucleus
Epsilon DNA Polymerase Complex
CHRAC
Molecular Function
DNA-directed DNA Polymerase Activity
Protein Binding
Chromatin DNA Binding
Protein Heterodimerization Activity
DNA Binding
DNA-directed DNA Polymerase Activity
Protein Binding
Protein Heterodimerization Activity
Biological Process
G1/S Transition Of Mitotic Cell Cycle
DNA Replication
DNA Replication Initiation
Leading Strand Elongation
Cellular Response To DNA Damage Stimulus
Heterochromatin Assembly
Telomere Maintenance Via Semi-conservative Replication
Nucleosome Mobilization
Histone H3 Acetylation
DNA Biosynthetic Process
Chromatin Remodeling
DNA Biosynthetic Process
Pathways
Recognition of DNA damage by PCNA-containing replication complex
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
DNA replication initiation
Activation of the pre-replicative complex
Drugs
Cladribine
Diseases
GWAS
Experiencing mood swings (
29500382
)
Interacting Genes
7 interacting genes:
APP
BAZ1A
CHRAC1
DR1
DRAP1
POLE4
SMARCA5
5 interacting genes:
APP
BAZ1A
FAM9B
POLE3
SMARCA5
Entrez ID
54107
54108
HPRD ID
06274
06275
Ensembl ID
ENSG00000148229
ENSG00000104472
Uniprot IDs
A0A024R829
Q9NRF9
Q9NRG0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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