PMM1 and RAB6B

Data Source:
BioGRID (two hybrid)

		PMM1	RAB6B
Description		phosphomannomutase 1	RAB6B, member RAS oncogene family
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GO Annotations	Cellular Component	Cytosol Neuronal Cell Body	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Endomembrane System Cytoplasmic Vesicle Presynapse
	Molecular Function	Phosphomannomutase Activity Protein Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Myosin V Binding
	Biological Process	Mannose Metabolic Process Protein N-linked Glycosylation GDP-mannose Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi
Pathways		Synthesis of GDP-mannose	COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Blood protein levels ( 30072576) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		5 interacting genes: CACNA1A MFHAS1 RAB6A RAB6B RCHY1	14 interacting genes: ACVR1 BICD2 BMPR1B COG6 ERC1 KIF20A LNX2 MEOX2 PMM1 RABGAP1 RAP1GDS1 SH2B2 SMAD1 TGFBR1
Entrez ID		5372	51560
HPRD ID		03473	11474
Ensembl ID		ENSG00000100417	ENSG00000154917
Uniprot IDs		A0A024R1U5 Q92871	Q9NRW1
PDB IDs		2FUC 2FUE 6CFR 6CFS 6CFT 6CFU 6CFV	2E9S 2FE4 2FFQ
Enriched GO Terms of Interacting Partners?
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