PLXNB1 and SEMA4B

Data Source:
HPRD (in vitro, in vivo)

		PLXNB1	SEMA4B
Description		plexin B1	semaphorin 4B
Image			No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Space Integral Component Of Plasma Membrane Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity GTPase Activator Activity Protein Binding Semaphorin Receptor Activity Semaphorin Receptor Binding GTPase Activating Protein Binding Signaling Receptor Activity	Semaphorin Receptor Binding Chemorepellent Activity
	Biological Process	Negative Regulation Of Cell Adhesion Signal Transduction G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Shape Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Migration Regulation Of Cell Migration Negative Regulation Of Osteoblast Proliferation Intracellular Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Ossification Involved In Bone Maturation Neuron Projection Morphogenesis Positive Regulation Of Axonogenesis Regulation Of Cytoskeleton Organization Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Bone Trabecula Morphogenesis Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Inhibitory Synapse Assembly	Neural Crest Cell Migration Axon Guidance Positive Regulation Of Cell Migration Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Semaphorin-plexin Signaling Pathway
Pathways		G alpha (12/13) signalling events Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Acne (severe) ( 30542056) Frontal fibrosing alopecia ( 30850646) Pulse pressure ( 27841878)
Interacting Genes		14 interacting genes: ARHGEF11 ARHGEF12 KMT2A L1CAM MET NRP1 NRP2 PLXNA1 RAC1 RND1 RND3 SEMA4B SEMA4D SOX4	4 interacting genes: CPEB2 DLG4 GIPC1 PLXNB1
Entrez ID		5364	10509
HPRD ID		03032	10217
Ensembl ID		ENSG00000164050	ENSG00000185033
Uniprot IDs		O43157	Q9NPR2
PDB IDs		2JPH 2OS6 2R2O 2REX 3HM6 3OL2 3SU8 3SUA 5B4W
Enriched GO Terms of Interacting Partners?
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