SERPINF2 and BCAP31

Data Source:
BioGRID (two hybrid)

		SERPINF2	BCAP31
Description		serpin family F member 2	B cell receptor associated protein 31
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Fibrinogen Complex Extracellular Space Cell Surface Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Integral Component Of Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Perinuclear Endoplasmic Reticulum
	Molecular Function	Protease Binding Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Protein Homodimerization Activity	Protein Binding MHC Class I Protein Binding Protein-containing Complex Binding
	Biological Process	Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Platelet Degranulation Acute-phase Response Response To Organic Substance Negative Regulation Of Plasminogen Activation Negative Regulation Of Endopeptidase Activity Collagen Fibril Organization Positive Regulation Of Collagen Biosynthetic Process Fibrinolysis Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of JNK Cascade Blood Vessel Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Fibrinolysis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Targeting To Mitochondrion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Spermatogenesis Viral Process Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Response To Endoplasmic Reticulum Stress Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Platelet degranulation Dissolution of Fibrin Clot	Apoptotic cleavage of cellular proteins Apoptotic execution phase Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		Ocriplasmin Copper
Diseases		Alpha-2-plasmin inhibitor (a2-PI) deficiency
GWAS		Blood protein levels ( 29875488) Calcium levels ( 24068962 20705733) Serum albumin level ( 23022100 29403010) Urate levels ( 31578528)
Interacting Genes		17 interacting genes: BCAP31 CFD CTRB1 DEFA1 ELANE F11 F13A1 FGA KLK13 KLK2 KLK6 PLAU PLG PRSS1 SERPINB12 SSR1 TGM2	30 interacting genes: ACTG1 APP AQP2 BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 CDC42 DRD2 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 LMAN1 MSN MYH10 PLP2 SERPINF2 TIMMDC1 TMEM31 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ
Entrez ID		5345	10134
HPRD ID		02029	02319
Ensembl ID		ENSG00000167711	ENSG00000185825
Uniprot IDs		P08697	P51572
PDB IDs			4JZL 4JZP
Enriched GO Terms of Interacting Partners?
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