PLD2 and ALDOC

Data Source:
HPRD (in vitro)

		PLD2	ALDOC
Description		phospholipase D2	aldolase, fructose-bisphosphate C
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Presynapse	Extracellular Region Cytosol Cytoskeleton Secretory Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Phospholipase D Activity Protein Binding Phosphatidylinositol Binding N-acylphosphatidylethanolamine-specific Phospholipase D Activity	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Cytoskeleton Organization Small GTPase Mediated Signal Transduction Lipid Catabolic Process Synaptic Vesicle Recycling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Inositol Lipid-mediated Signaling Cell Motility	Fructose Metabolic Process Gluconeogenesis Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Epithelial Cell Differentiation Neutrophil Degranulation Canonical Glycolysis
Pathways		Synthesis of PG Synthesis of PA Role of phospholipids in phagocytosis	Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs		Choline Choline salicylate
Diseases
GWAS		Sphingolipid levels ( 22359512) Systemic lupus erythematosus ( 26502338)
Interacting Genes		29 interacting genes: ACTB ACTN1 ALDOA ALDOC AMPH AQP3 ARF1 BIN1 CAV1 CSK DPYSL2 EGFR FYN GAPDH GM2A HIF1A LCK MTDH MTOR OPRM1 PEA15 PIP5K1A PLCG1 PRKCA PRKCD RPTOR SRC STXBP1 VHL	7 interacting genes: ANKS1A ATP6V1E1 ERBB2 LNX1 MAP2K3 PLD2 SQLE
Entrez ID		5338	230
HPRD ID		03857	02386
Ensembl ID		ENSG00000129219	ENSG00000109107
Uniprot IDs		O14939	A0A024QZ64 P09972
PDB IDs		6OHM 6OHO 6OHP 6OHQ 6OHS	1XFB
Enriched GO Terms of Interacting Partners?
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