ALDOC and PLD2

Data Source:
HPRD (in vitro)

		ALDOC	PLD2
Description		aldolase, fructose-bisphosphate C	phospholipase D2
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Cytoskeleton Secretory Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Endoplasmic Reticulum Membrane Plasma Membrane Presynapse
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding	Phospholipase D Activity Protein Binding Phosphatidylinositol Binding N-acylphosphatidylethanolamine-specific Phospholipase D Activity
	Biological Process	Fructose Metabolic Process Gluconeogenesis Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Epithelial Cell Differentiation Neutrophil Degranulation Canonical Glycolysis	Phosphatidic Acid Biosynthetic Process Cytoskeleton Organization Small GTPase Mediated Signal Transduction Lipid Catabolic Process Synaptic Vesicle Recycling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Inositol Lipid-mediated Signaling Cell Motility
Pathways		Neutrophil degranulation Glycolysis Gluconeogenesis	Synthesis of PG Synthesis of PA Role of phospholipids in phagocytosis
Drugs			Choline Choline salicylate
Diseases
GWAS			Sphingolipid levels ( 22359512) Systemic lupus erythematosus ( 26502338)
Interacting Genes		7 interacting genes: ANKS1A ATP6V1E1 ERBB2 LNX1 MAP2K3 PLD2 SQLE	29 interacting genes: ACTB ACTN1 ALDOA ALDOC AMPH AQP3 ARF1 BIN1 CAV1 CSK DPYSL2 EGFR FYN GAPDH GM2A HIF1A LCK MTDH MTOR OPRM1 PEA15 PIP5K1A PLCG1 PRKCA PRKCD RPTOR SRC STXBP1 VHL
Entrez ID		230	5338
HPRD ID		02386	03857
Ensembl ID		ENSG00000109107	ENSG00000129219
Uniprot IDs		A0A024QZ64 P09972	O14939
PDB IDs		1XFB	6OHM 6OHO 6OHP 6OHQ 6OHS
Enriched GO Terms of Interacting Partners?
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