PKNOX1 and FAM110B

Data Source:
BioGRID (two hybrid)

		PKNOX1	FAM110B
Description		PBX/knotted 1 homeobox 1	family with sequence similarity 110 member B
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Mitochondrion Microtubule Organizing Center Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)	Bipolar disorder and schizophrenia ( 20889312) Blood pressure measurement (low sodium intervention) ( 24165912) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Pit-and-Fissure caries ( 24556642) Shingles ( 30298529) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		23 interacting genes: APP BLOC1S5 BORCS6 FAM110B FHL2 HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 MPP3 NUP58 PAX6 PBX1 PBX2 PBX4 POU2F1 RFX3 TET2 TLX1 VPS37C ZBTB3	5 interacting genes: HSF2BP MEIS3 PKNOX1 PKNOX2 RHOU
Entrez ID		5316	90362
HPRD ID		03653	14609
Ensembl ID		ENSG00000160199	ENSG00000169122
Uniprot IDs		B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87	A0A024R7V5 B3KRT5 Q8TC76
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?
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