PKNOX1 and HOXB6

Data Source:
HPRD (in vivo)

		PKNOX1	HOXB6
Description		PBX/knotted 1 homeobox 1	homeobox B6
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Erythrocyte Homeostasis Embryonic Skeletal System Morphogenesis
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)	Childhood body mass index ( 26604143) Hemoglobin ( 32888494)
Interacting Genes		23 interacting genes: APP BLOC1S5 BORCS6 FAM110B FHL2 HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 MPP3 NUP58 PAX6 PBX1 PBX2 PBX4 POU2F1 RFX3 TET2 TLX1 VPS37C ZBTB3	17 interacting genes: ALX4 CLK3 CREBBP CSNK2B EP300 GYS1 HOXB7 KRT15 NEK6 NTAQ1 PKNOX1 PLSCR1 SAT1 SRPK2 TCEAL1 TCF21 TEKT5
Entrez ID		5316	3216
HPRD ID		03653	00849
Ensembl ID		ENSG00000160199	ENSG00000108511
Uniprot IDs		B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87	P17509
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?
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