PIGC and DPM2

Data Source:
HPRD (in vitro)

		PIGC	DPM2
Description		phosphatidylinositol glycan anchor biosynthesis class C	dolichyl-phosphate mannosyltransferase subunit 2, regulatory
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Dolichol-phosphate-mannose Synthase Complex
	Molecular Function	Catalytic Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Protein Binding Enzyme Activator Activity Enzyme Regulator Activity
	Biological Process	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Protein N-linked Glycosylation Via Asparagine Dolichol Metabolic Process Regulation Of Protein Stability Protein O-linked Mannosylation Regulation Of Catalytic Activity
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)	Synthesis of dolichyl-phosphate mannose Synthesis of glycosylphosphatidylinositol (GPI) Defective DPM1 causes DPM1-CDG (CDG-1e) Defective DPM3 causes DPM3-CDG (CDG-1o) Defective DPM2 causes DPM2-CDG (CDG-1u)
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Hemoglobin levels ( 32327693) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Body mass index ( 26426971) Glaucoma (primary angle closure) ( 27064256)
Interacting Genes		4 interacting genes: DPM2 KLF10 PIGQ ZHX1	7 interacting genes: DPM1 DPM3 HLA-DMB PIGA PIGC SLC22A2 VKORC1
Entrez ID		5279	8818
HPRD ID		03433	16028
Ensembl ID		ENSG00000135845	ENSG00000136908
Uniprot IDs		Q92535	O94777
PDB IDs
Enriched GO Terms of Interacting Partners?
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