SERPINA4 and KLK1

		SERPINA4	KLK1
Description		serpin family A member 4	kallikrein 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Dense Granule Lumen Extracellular Exosome	Nucleus Secretory Granule Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity	Serine-type Endopeptidase Activity
	Biological Process	Platelet Degranulation Negative Regulation Of Endopeptidase Activity	Regulation Of Systemic Arterial Blood Pressure Zymogen Activation
Pathways		Platelet degranulation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs		Zinc Copper Zinc acetate	Aluminium Benzamidine Lanoteplase Aprotinin Aniline Nafamostat Aluminium phosphate Aluminum acetate
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Vaspin levels ( 22907691)	Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)
Interacting Genes		13 interacting genes: CTSD GADD45G ILK KLK1 KLK2 MAP4K2 MAPK6 NR4A1 RASA1 TAB1 TNFRSF14 TNNT1 YAE1	8 interacting genes: A2M ITIH4 KNG1 PROC SERPINA1 SERPINA4 SERPINA5 SERPINC1
Entrez ID		5267	3816
HPRD ID		01004	01003
Ensembl ID		ENSG00000100665	ENSG00000167748
Uniprot IDs		A0A024R6I9 P29622	A0A1L2BPJ2 A0A1R3UCD2 P06870
PDB IDs		6F02	1SPJ
Enriched GO Terms of Interacting Partners?
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