PER1 and LTB4R2

Data Source:
BioGRID (two hybrid)

		PER1	LTB4R2
Description		period circadian regulator 1	leukotriene B4 receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding Protein Binding Kinase Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding E-box Binding	Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Sodium Ion Transport Circadian Rhythm Entrainment Of Circadian Clock Posttranscriptional Regulation Of Gene Expression Circadian Regulation Of Gene Expression Regulation Of Hair Cycle Regulation Of Circadian Rhythm Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Entrainment Of Circadian Clock By Photoperiod Histone H3 Acetylation Histone H4 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of JNK Cascade Response To CAMP Histone H3 Deacetylation Circadian Regulation Of Translation Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of P38MAPK Cascade Negative Regulation Of Glucocorticoid Receptor Signaling Pathway	Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Leukotriene Signaling Pathway
Pathways		Circadian Clock	Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases
GWAS		HDL cholesterol levels ( 32203549) High light scatter reticulocyte percentage of red cells ( 32888494)	Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		19 interacting genes: CCDC57 CRY1 CRY2 CSNK1D CSNK1E CSNK1G2 CSNK2B DELEC1 GPRASP1 HIF1A LTB4R2 PER2 PER3 PNMA1 RBPMS RIPOR2 TIMELESS TNS2 TRIP6	46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		5187	56413
HPRD ID		03774	16153
Ensembl ID		ENSG00000179094	ENSG00000213906
Uniprot IDs		O15534	B4E292 Q9NPC1
PDB IDs		1UL6
Enriched GO Terms of Interacting Partners?
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