LTB4R2 and MGLL

Data Source:
BioGRID (two hybrid)

		LTB4R2	MGLL
Description		leukotriene B4 receptor 2	monoglyceride lipase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane	Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Extrinsic Component Of Membrane
	Molecular Function	Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity	Lysophospholipase Activity Protein Binding Lipase Activity Protein Homodimerization Activity Acylglycerol Lipase Activity
	Biological Process	Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Leukotriene Signaling Pathway	Lipid Metabolic Process Fatty Acid Biosynthetic Process Inflammatory Response Regulation Of Signal Transduction Arachidonic Acid Metabolic Process Triglyceride Catabolic Process Acylglycerol Acyl-chain Remodeling Acylglycerol Catabolic Process Regulation Of Inflammatory Response Regulation Of Sensory Perception Of Pain Monoacylglycerol Catabolic Process Regulation Of Endocannabinoid Signaling Pathway
Pathways		Leukotriene receptors G alpha (q) signalling events	Acyl chain remodeling of DAG and TAG Triglyceride catabolism Arachidonate production from DAG
Drugs		Amelubant Leukotriene B4
Diseases
GWAS		Anorectal malformation ( 31136621) Height ( 28552196)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid intima media thickness x smoking interaction ( 32117412) Pars triangularis volume ( 31530798) Refractive error ( 32231278)
Interacting Genes		46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B	25 interacting genes: ADRB2 AQP6 CD79A CHGB COQ9 EBAG9 FAM209A FCER1G GEM GOLT1A GPR152 HSD17B13 HTR4 LMNA LTB4R2 MFSD14B MSRB3 PEX12 SDCBP SLC10A6 SLC66A2 SLC7A14 STOM TMEM35A TMX2
Entrez ID		56413	11343
HPRD ID		16153	17574
Ensembl ID		ENSG00000213906	ENSG00000074416
Uniprot IDs		B4E292 Q9NPC1	A0A0C4DFN3 B2ZGL7 E7EWX8 Q99685
PDB IDs			3HJU 3JW8 3JWE 3PE6 4UUQ 5ZUN 6AX1 6BQ0
Enriched GO Terms of Interacting Partners?
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