CD244 and CD48

Data Source:
HPRD (in vivo, in vitro)

		CD244	CD48
Description		CD244 molecule	CD48 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding	Antigen Binding Protein Binding Signaling Receptor Activity
	Biological Process	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Signal Transduction Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Leukocyte Migration Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production	Regulation Of Adaptive Immune Response Defense Response Leukocyte Migration
Pathways		Cell surface interactions at the vascular wall	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)	Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		5 interacting genes: ARHGEF7 CD247 CD48 LAT SH2D1B	10 interacting genes: BRIX1 CD2 CD244 CD247 EEF1D FYN GNAI3 IL18R1 IL18RAP LCK
Entrez ID		51744	962
HPRD ID		16121	00177
Ensembl ID		ENSG00000122223	ENSG00000117091
Uniprot IDs		Q9BZW8	A0A087X1S7 P09326
PDB IDs			2EDO
Enriched GO Terms of Interacting Partners?
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