PDZK1 and SLCO1A2

Data Source:
HPRD (two hybrid)

		PDZK1	SLCO1A2
Description		PDZ domain containing 1	solute carrier organic anion transporter family member 1A2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding	Organic Anion Transmembrane Transporter Activity Bile Acid Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity
	Biological Process	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Organic Anion Transport Bile Acid And Bile Salt Transport Sodium-independent Organic Anion Transport Transmembrane Transport
Pathways			Recycling of bile acids and salts Transport of organic anions
Drugs
Diseases
GWAS		Contrast sensitivity ( 24152035) Gout ( 32238385) Serum uric acid levels ( 30993211) Urate levels ( 31985003 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)	AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875) Bilirubin levels ( 19414484) Diisocyanate-induced asthma ( 25918132) Methotrexate phramacokinetics (acute lymphoblastic leukemia) ( 19901119) Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Progressive supranuclear palsy ( 30089514 21685912) Serum metabolite levels ( 23093944) Statin-induced myopathy (severe) ( 31220337)
Interacting Genes		31 interacting genes: ABCA1 ABCC2 ABCC4 ACE2 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC13A1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	4 interacting genes: PDZD3 PDZK1 SLC9A3R1 SLC9A3R2
Entrez ID		5174	6579
HPRD ID		04829	09112
Ensembl ID		ENSG00000174827	ENSG00000084453
Uniprot IDs		Q5T2W1	A0A024RAT5 P46721
PDB IDs		2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI
Enriched GO Terms of Interacting Partners?
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