LSM7 and SART3

Data Source:
BioGRID (fluorescent resonance energy transfer, affinity chromatography technology)

		LSM7	SART3
Description		LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated	spliceosome associated factor 3, U4/U6 recycling protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm U6atac SnRNP Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex ASAP Complex U4/U6 SnRNP U4atac/U6atac SnRNP
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	RNA Binding Protein Binding U6 SnRNA Binding U4 SnRNA Binding U6atac SnRNA Binding Histone Binding Ubiquitin-specific Protease Binding
	Biological Process	MRNA Splicing, Via Spliceosome Exonucleolytic Catabolism Of Deadenylated MRNA	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Nucleosome Assembly Regulation Of Gene Expression Positive Regulation Of Histone Deubiquitination
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases			Disseminated superficial actinic porokeratosis (DSAP)
GWAS		Parkinson's disease ( 28892059)	Acne (severe) ( 24927181)
Interacting Genes		25 interacting genes: DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SART3 SMN1 SNRPD3 SNRPF SYT17 TACC1 TCL1B ZSCAN26	29 interacting genes: AR C6 COIL H2AC20 H2BC21 KPNA2 LSM7 MEGF10 MIR1-1 MIR128-2 MIR143 MIR18A MIR18B MIR19B2 MIR200B MIR200C MIR221 MIR34A MIR34B MIR7-1 MIR7-3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 PRPF3 RNPS1 ZNF620 ZNF71
Entrez ID		51690	9733
HPRD ID		06287	11532
Ensembl ID		ENSG00000130332	ENSG00000075856
Uniprot IDs		Q9UK45	A0A499FI31 Q15020
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	2DO4 5CTQ 5CTR 5CTT 5JJW 5JJX 5JPZ
Enriched GO Terms of Interacting Partners?
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